Combining AI-powered mRNA design with non-viral delivery to achieve organ-specific targeting
Claire Guéguen, Davide De Lucrezia
15 July 2025
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Accelerate UF/DF of nucleic acids with real-time monitoring and automated process control
Nigel Herbert
10 July 2025
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Oligonucleotide manufacturing innovation: challenges, risks, and opportunities
Barrie Cassey
27 June 2025
Expert Insight
Targeting brain delivery of lipid and polymer nanoparticle-based gene therapies with Sunshine
Benjamin Knappett, Nutan Bhingaradiya, Mahima Dewani
26 June 2025
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Overcoming mRNA medicine supply hurdles: distributed, continuous and multi-product mRNA manufacturing in a box at high quality and low cost
Bojan Kopilovic, Mabrouka Maamra, Zoltán Kis
20 June 2025
Expert Insight
Optimizing plasmid DNA purification: strategies for reliable and expandable processes
Christy Franco, Jasmina Puc
17 June 2025
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Assessing mRNA stability and integrity using mass photometry
Maria Jacintha Victoria
04 June 2025
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Precise mRNA purity assessment for accelerated therapeutic development and release testing
Paul Mania, Joe Ferraiolo
04 June 2025
Webinar Digest
Incorporating digitalization in the conceptual design, research and development of plasmid biomanufacturing
D Prazeres, A Azevedo, S Oliveira Duarte et al
29 May 2025
Commentary
Find the EV needle in the haystack with Leprechaun
Kevin Lance
22 May 2025
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AI-driven modular platform for peptide dendrimer lipid nanocarriers: streamlining and accelerating precision nucleic acid delivery
Tristan Henser-Brownhill, Albert Kwok
22 May 2025
Viewpoint
Enhancing manufacturing efficiency and quality through optimized lysis in plasmid DNA extraction
Robin Pelizzari, Matevž Korenč
21 May 2025
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Producing low-immunogenicity, high-stability mRNA with dsRNA reduction to <0.005% (LLOQ)
Jen Dennin
21 May 2025
FastFacts
A case study in faster, higher-quality pDNA manufacturing
Xiangming Gu, Lucas Smith
20 May 2025
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Revolutionizing non-viral gene delivery with silicon-stabilized LNPs
Suzanne Saffie-Siebert
20 May 2025
Interview
Exploring the latest advances in purification and analysis of oligonucleotide therapeutics
Patrick Endres, Martin Kögler
15 May 2025
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Optimizing mRNA production: achieving 25 g/L mRNA yield with low dsRNA by integrating PAT
Rok Sekirnik
08 May 2025
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07 May 2025
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Solving unique analytical challenges in mRNA-LNP bioprocessing with precise measurement methods
Nigel Herbert
01 May 2025
Innovator Insight
Meet the Nucleic Acid Insights Editorial Board
V Linko, Y Chen, J Counsell et al
30 April 2025
Infographic
What are your top predictions for the next five years in the nucleic acids field?
J Yan, P Kowalski, J Weterings et al
30 April 2025
The Big Question