mRNA

Incorporating digitalization in the conceptual design, research and development of plasmid biomanufacturing

Incorporating digitalization in the conceptual design, research and development of plasmid biomanufacturing

D Prazeres, A Azevedo, S Oliveira Duarte et al

AI-driven modular platform for peptide dendrimer lipid nanocarriers: streamlining and accelerating precision nucleic acid delivery

AI-driven modular platform for peptide dendrimer lipid nanocarriers: streamlining and accelerating precision nucleic acid delivery

Tristan Henser-Brownhill, Albert Kwok

Producing low-immunogenicity, high-stability mRNA with dsRNA reduction to <0.005% (LLOQ)

Producing low-immunogenicity, high-stability mRNA with dsRNA reduction to <0.005% (LLOQ)

Solving unique analytical challenges in mRNA-LNP bioprocessing with precise measurement methods

Solving unique analytical challenges in mRNA-LNP bioprocessing with precise measurement methods

Innovator Insight

Meet the Nucleic Acid Insights Editorial Board

Meet the Nucleic Acid Insights Editorial Board

V Linko, Y Chen, J Counsell et al

What are your top predictions for the next five years in the nucleic acids field?

What are your top predictions for the next five years in the nucleic acids field?

J Yan, P Kowalski, J Weterings et al

The Big Question

Meet the Nucleic Acids Insights Editorial Board: Nizar Y Saad

Meet the Nucleic Acids Insights Editorial Board: Nizar Y Saad

The future is now: AI-enabled RNA–LNP discovery

The future is now: AI-enabled RNA–LNP discovery

Novel srRNA vectors for customizable vaccine development

Novel srRNA vectors for customizable vaccine development

D S Spasova, S J Miyake-Stoner, G Picarda et al

Short Communication

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Optimizing plasmid DNA purification: strategies for reliable and expandable processes

Optimizing plasmid DNA purification: strategies for reliable and expandable processes

Christy Franco, Jasmina Puc

Assessing mRNA stability and integrity using mass photometry

Assessing mRNA stability and integrity using mass photometry

Maria Jacintha Victoria

Optimizing mRNA production: achieving 25 g/L mRNA yield with low dsRNA by integrating PAT

Optimizing mRNA production: achieving 25 g/L mRNA yield with low dsRNA by integrating PAT

Exploring mRNA quality assessment using electrophoretic separation methods

Exploring mRNA quality assessment using electrophoretic separation methods

Chateen Krueger

A scalable purification strategy for removal of dsRNA byproducts following IVT RNA production

A scalable purification strategy for removal of dsRNA byproducts following IVT RNA production

Nathaniel Clark

Achieving high-quality, efficient mRNA synthesis for streamlined and cost-effective manufacturing

Achieving high-quality, efficient mRNA synthesis for streamlined and cost-effective manufacturing

Helge Zieler, Khaled Yamout

Next-level LNP formulation with the Sunny Suite

Next-level LNP formulation with the Sunny Suite

Benjamin Knappett

Sharpen up your RNA and LNP quant with Stunner

Sharpen up your RNA and LNP quant with Stunner

Solving unique analytical challenges in mRNA-LNP bioprocessing with precise measurement methods

Solving unique analytical challenges in mRNA-LNP bioprocessing with precise measurement methods

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