Assessing mRNA stability and integrity using mass photometry

Wednesday 08:00 PDT / 11:00 EDT / 16:00 BST / 17:00 CEST

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Assessing mRNA stability and integrity using mass photometry

Live30 webinars are thirty-minute presentations designed to update you on the latest innovations, applications, and data in a fast yet interactive format.

Mass photometry is a rapid, cost-effective, and user-friendly technique for RNA characterization that offers a powerful alternative to traditional methods by directly measuring molecular mass. This technique enables the study of large heterogeneous mRNA without denaturation, digestion, or online separation, providing a rapid, sensitive, and reliable analytical method for assessing RNA stability, sizing, and purity.

We will present quantitative results from inhibitor binding studies using mass photometry. Attendees will find out how to implement mass photometry-based workflows for rapid assessment of RNA integrity, enabling faster troubleshooting and quality checks in RNA production or research. Adopting a label-free strategy for monitoring mRNA stability reduces reliance on traditional, time-consuming assays like gel electrophoresis or chromatography.

Find out how to overcome common RNA analysis bottlenecks by learning how mass photometry simplifies workflows—no denaturation, labelling, or complex prep required
Improve data confidence and decision-making with a reliable method to assess mRNA stability and integrity in minutes, not hours or days
Stay ahead of industry trends by exploring how cutting-edge, label-free technologies are reshaping RNA therapeutic development and quality control
Discover how to apply mass photometry to evaluate small molecule interactions with RNA, supporting early-stage screening and drug development efforts with quantitative binding data

Maria Jacintha Victoria

Market Development Manger (CGT) at Refeyn Ltd

Jacintha Victoria is a strategic marketing and analytical leader with over a decade of experience in the biotechnology and gene therapy sectors. As the Market Development Manager at Refeyn Ltd. in Oxford, UK, she leads initiatives/ campaigns to drive the adoption of Mass Photometry across critical applications in cell and gene therapy, including AAV, LVV, adenovirus, and RNA-based platforms. With a deep understanding of the emerging analytical technologies, Jacintha advocates for Mass Photometry as a transformative tool to enhance viral vector characterization, accelerate product development, and strengthen regulatory preparedness. She holds a Master of Science in Cellular and Molecular Biology from the University of New Haven and is certified as a Technologist in Molecular Biology by the ASCP. Passionate about bridging science and strategy, Jacintha is dedicated to advancing innovative therapeutic solutions through data-driven marketing, cross-functional collaboration, and thought leadership.

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