Accelerate your AAV process development with a new-wave analytical tool

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Accelerate your AAV process development with a new-wave analytical tool

Adeno-associated viruses (AAVs) are widely used vectors for gene therapies, mainly due to their favorable safety profile and high transduction efficiency to various target tissues. With increasing demand for faster process development of advanced therapies using AAVs, rapid at-line analytical chromatographic solutions are becoming indispensable.

PATfix™ analytical system with multiple detectors seamlessly delivers coherent process information, considerably speeding up process development and enabling a fast-paced delivery of the product to the market.

Analytical methods embedded in the PATfix™ system enable at-line monitoring of common product- and process-related impurities and provide a critical platform for the rapid development and characterization of AAV-based gene therapy vectors.

Analytical platform to support process development and product QC
Analytical method for E/F separation
Monitoring impurities and final product analysis
Analytical platform with multiple detector setup

Andreja Gramc Livk

Head of Process Analytics Development Sartorius BIA Separations

Andreja is a Head of Process Analytics Development department at Sartorius BIA Separations. She leads process analytics development team that focuses on the further advancement of a PATfixTM HPLC solutions, involving the development of innovative methods for the analysis of biological molecules, including mRNA, pDNA and viruses. Over the course of career with biotech companies, she gained a wide range experience in protein chemistry, including characterisation of biosimilars and biologics. She holds a Master Science in Biochemistry from the University of Ljubljana, Slovenia.

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