BioInsights - Webinars

CELL AND GENE THERAPY INSIGHTS

Upcoming webinars

Maintaining cell health and viability in cell processing

Maintaining cell health and viability in cell processing

Josh Judkins
28 September
Today
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Alleviating production bottlenecks in AAV manufacture via platform innovation

Alleviating production bottlenecks in AAV manufacture via platform innovation

Weiheng Su, Matt Roach
3 October
in 6
Days
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The growing case for stainless steel versus single-use in mRNA vaccine production

The growing case for stainless steel versus single-use in mRNA vaccine production

Steve Attig
4 October
in 7
Days
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Cell sorting for enrichment of neuronal subpopulations – new perspectives for clinical research

Cell sorting for enrichment of neuronal subpopulations – new perspectives for clinical research

Thomas Andreska, E Nent, C Jin
5 October
in 8
Days
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Case study: becoming the first GMP-certified cell and gene therapy manufacturing facility in Thailand

Case study: becoming the first GMP-certified cell and gene therapy manufacturing facility in Thailand

Kitipong Uaesoontrachoon
10 October
in 13
Days
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Live lab demo: unlock the future of vaccine analysis with CTech SoloVPE

Live lab demo: unlock the future of vaccine analysis with CTech SoloVPE

Paul Mania, Nigel Herbert
11 October
in 14
Days
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New empty/full method to enable robust manufacturing of AAV products

New empty/full method to enable robust manufacturing of AAV products

Aleš Štrancar
12 October
in 15
Days
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Unlocking allogeneic cell therapy success: downstream strategies for commercialization

Unlocking allogeneic cell therapy success: downstream strategies for commercialization

J Lee, T Nanda, N Tyagi
17 October
in 20
Days
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Redefining extracellular vesicle production: proof of concept study evaluating structured fixed-bed bioreactor for high-capacity production

Redefining extracellular vesicle production: proof of concept study evaluating structured fixed-bed bioreactor for high-capacity production

Effie Huang, Stephen Lenzini
18 October
in 21
Days
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Simplifying residual DNA quantitation in biotherapeutic manufacturing

Simplifying residual DNA quantitation in biotherapeutic manufacturing

Ilaria Scarfone
19 October
in 22
Days
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Advancing clinical-grade tumor-infiltrating lymphocyte therapy manufacturing

Advancing clinical-grade tumor-infiltrating lymphocyte therapy manufacturing

Arina Riabinska
24 October
in 27
Days
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Fine-tuning your mRNA-LNP formulation with an innovative cationic lipid library

Fine-tuning your mRNA-LNP formulation with an innovative cationic lipid library

Nathan Chaboche, Quentin Huaulmé
25 October
in 28
Days
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Meeting the needs for large scale expansion and processing of clinically relevant numbers of functional human NK cells

Meeting the needs for large scale expansion and processing of clinically relevant numbers of functional human NK cells

Erica Heipertz
26 October
in 29
Days
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Establishing the first southern Chinese haplobank of clinical-grade hiPSCs

Establishing the first southern Chinese haplobank of clinical-grade hiPSCs

Camie Chan, Chao Sheng
31 October
in 34
Days
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De-risking cell therapy product development: strategies for commercial success

De-risking cell therapy product development: strategies for commercial success

Chad Andersen
7 November
in 41
Days
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New methods to separate empty, partial, full and heavy AAV capsids

New methods to separate empty, partial, full and heavy AAV capsids

Aleš Štrancar
8 November
in 42
Days
Register

On demand webinars

Expert roundtable: Exploring current and future trends in lentiviral vector manufacturing

Expert roundtable: Exploring current and future trends in lentiviral vector manufacturing

A Vernon, P Palaniappan, P Vanek et al.
27 September
Watch
Pushing the boundaries of LNP production: an innovative analytical platform for evaluating vital LNP characteristics

Pushing the boundaries of LNP production: an innovative analytical platform for evaluating vital LNP characteristics

Nejc Pavlin
26 September
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Empowering the future of cell therapy: leveraging partnerships to support advancement

Empowering the future of cell therapy: leveraging partnerships to support advancement

J Patarroyo, F Mack, X de Mollerat du Jeu et al.
21 September
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Considerations for affinity capture in an AAV platform downstream process

Considerations for affinity capture in an AAV platform downstream process

Jett Appel
20 September
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Scaling cell & gene therapy operations with Industry 4.0

Scaling cell & gene therapy operations with Industry 4.0

Ryan Thompson, Peter Walters
19 September
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Achieving flexibility and scalability in cell therapy manufacturing through optimized cell isolation and activation

Achieving flexibility and scalability in cell therapy manufacturing through optimized cell isolation and activation

Eugene Kang
14 September
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Beyond mRNA - how advances in analytical techniques are enabling a revolution of the RNA drug landscape

Beyond mRNA - how advances in analytical techniques are enabling a revolution of the RNA drug landscape

Andrew Geall
13 September
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Hollow fiber bioreactor: flexibility across modalities

Hollow fiber bioreactor: flexibility across modalities

M Miller, A Cunningham, N Frank
13 September
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Strategies to accelerate AAV chromatography process development

Strategies to accelerate AAV chromatography process development

Kelley Kearns
12 September
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How patient focus drives clinical trial results: the intersection of sponsor, CRO, site, and patient

How patient focus drives clinical trial results: the intersection of sponsor, CRO, site, and patient

K Kane, K Nealon, B Bratrude et al.
7 September
Watch
Accelerating analysis of viral vector titer, process impurities, and contaminants

Accelerating analysis of viral vector titer, process impurities, and contaminants

J Chappell, J Norton, I Osorio Querejeta et al.
6 September
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Enhancing non-viral genome editing and manufacturing of T and NK cells for immunotherapies

Enhancing non-viral genome editing and manufacturing of T and NK cells for immunotherapies

Ilgyun Im, Rebecca Lim
6 September
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How to increase AAV production with a novel enhancer designed for use with any transfection reagent in any suspension HEK cell

How to increase AAV production with a novel enhancer designed for use with any transfection reagent in any suspension HEK cell

Leisha Kopp
5 September
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Expand your T cell manufacturing capacities in an automated, closed system to shorten your production time

Expand your T cell manufacturing capacities in an automated, closed system to shorten your production time

Sophia Lollies, Ian Johnston
31 August
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Streamlining vaccine development and production with modality-specific purification tools for mRNA and beyond

Streamlining vaccine development and production with modality-specific purification tools for mRNA and beyond

Eugene Sun
30 August
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Allogeneic cell therapy production trends: driving tomorrow’s success

Allogeneic cell therapy production trends: driving tomorrow’s success

Tom Bongiorno
29 August
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Establishing the standards of operational excellence to manufacture commercial cell therapies

Establishing the standards of operational excellence to manufacture commercial cell therapies

Hui Zheng, Melanie Mansbach
24 August
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Achieving vaccine equity: challenges and opportunities of multi-modality manufacturing

Achieving vaccine equity: challenges and opportunities of multi-modality manufacturing

Katarina Stenklo
23 August
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Solutions for clinical-grade manufacturing of gene-engineered NK cells

Solutions for clinical-grade manufacturing of gene-engineered NK cells

Maria Delso Vallejo
22 August
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Harnessing mass photometry for AAV sample characterization in GMP-regulated environments

Harnessing mass photometry for AAV sample characterization in GMP-regulated environments

Cátia Crespo
15 August
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AAV and lentiviral titer determination - past, present, and future

AAV and lentiviral titer determination - past, present, and future

J Bechill, P Wang, M White
10 August
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Better mRNA-LNPs: encapsulation efficiency, mRNA integrity and purity, lipid N-oxides, and beyond

Better mRNA-LNPs: encapsulation efficiency, mRNA integrity and purity, lipid N-oxides, and beyond

Jane Luo
9 August
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AAV vectors in a spin: zonal ultracentrifugation as an effective, automated and scalable downstream processing methodology

AAV vectors in a spin: zonal ultracentrifugation as an effective, automated and scalable downstream processing methodology

Sandra Meriño, Seth Brittle
3 August
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Expanding access to gene therapies through novel cell lines and dPCR technologies

Expanding access to gene therapies through novel cell lines and dPCR technologies

J Loganathan, A Noyszewski, M Voigt
1 August
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Targeting EGFR to enhance NKT cell-mediated killing of lung cancer cells

Targeting EGFR to enhance NKT cell-mediated killing of lung cancer cells

T J Webb, D Ferrick, S Chvatal
27 July
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Three distinct analytical ultracentrifugation methods for virus and viral vector characterizations

Three distinct analytical ultracentrifugation methods for virus and viral vector characterizations

Susumu Uchiyama
27 July
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Utilizing an automation-on-demand analytical tool for cancer immunotherapy

Utilizing an automation-on-demand analytical tool for cancer immunotherapy

Christoph Eberle
26 July
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Accelerate your AAV process development with a new-wave analytical tool

Accelerate your AAV process development with a new-wave analytical tool

Andreja Gramc Livk
26 July
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Exploring and overcoming the challenges of cell and gene-modified cell therapy CMC

Exploring and overcoming the challenges of cell and gene-modified cell therapy CMC

J Sable, L Bellot, K Doucette
25 July
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Regulatory considerations and validation strategies for mycoplasma testing for cell-based therapies

Regulatory considerations and validation strategies for mycoplasma testing for cell-based therapies

Michael Brewer
20 July
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Aldevron case study: validation of mRNA concentration determination using variable pathlength spectroscopy

Aldevron case study: validation of mRNA concentration determination using variable pathlength spectroscopy

J Ferraiolo, T Alvine, J Long
12 July
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Early-stage considerations for accelerating cell and gene therapy commercialization

Early-stage considerations for accelerating cell and gene therapy commercialization

Sabrina Carmichael
11 July
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Overcoming challenges in scaled manufacturing of iPSC-derived cells

Overcoming challenges in scaled manufacturing of iPSC-derived cells

A Steinbach, D Mann, M Diakatou et al.
6 July
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Addressing regulatory guidance for HEK293 cells and AAV-based therapeutic manufacturing

Addressing regulatory guidance for HEK293 cells and AAV-based therapeutic manufacturing

Michael Brewer
29 June
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A shortcut through process development for CAR-T cell manufacturing

A shortcut through process development for CAR-T cell manufacturing

Marko Gogala
27 June
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Accelerating your gene therapy to patients: not all platforms are created equal

Accelerating your gene therapy to patients: not all platforms are created equal

George Buchman, Thomas VanCott
22 June
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How reducing labor time can save on your cell therapy manufacturing costs

How reducing labor time can save on your cell therapy manufacturing costs

Y Kong, J Kang, J Schoep
21 June
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Scalable production of AAV from shake flasks to 1,000 L single use bioreactors using the Gibco™ CTS™ AAV-MAX Production System

Scalable production of AAV from shake flasks to 1,000 L single use bioreactors using the Gibco™ CTS™ AAV-MAX Production System

Jonathan Zmuda
20 June
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Overcoming upstream and downstream process barriers for large scale AAV production

Overcoming upstream and downstream process barriers for large scale AAV production

B Woo, A Miller, J Zmuda
15 June
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Enabling RNA therapeutics: innovative cationic lipids to improve LNP formulation

Enabling RNA therapeutics: innovative cationic lipids to improve LNP formulation

C Gueguen, M Hellal, J Depollier
14 June
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How can the gene therapy industry drive down the cost of goods to better serve patients?

How can the gene therapy industry drive down the cost of goods to better serve patients?

Emmanuelle Cameau
13 June
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How to increase speed from project initiation to IND filing for CGT products

How to increase speed from project initiation to IND filing for CGT products

Jennifer Cheung
8 June
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Leveraging the experience of cord blood banking in the development of cellular therapies

Leveraging the experience of cord blood banking in the development of cellular therapies

H Stefanski, M Finney, C Melief et al.
7 June
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Optimizing the cell therapy patient journey through integrated CRO/CDMO partnership

Optimizing the cell therapy patient journey through integrated CRO/CDMO partnership

Panteli Theocharous, Rupa Pike
6 June
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Improving AAV and LV upstream manufacturing using cGMP lipid polymer nanocomplexes (LPNCs)

Improving AAV and LV upstream manufacturing using cGMP lipid polymer nanocomplexes (LPNCs)

Leisha Kopp
1 June
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Cell therapy workflows: improving reproducibility and simplifying compliance efforts with batch centrifugation solutions

Cell therapy workflows: improving reproducibility and simplifying compliance efforts with batch centrifugation solutions

Atalay Tok
31 May
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Future-proof your AAV process with a complete producer cell line – just induce and grow

Future-proof your AAV process with a complete producer cell line – just induce and grow

Dovile Gruzdyte
25 May
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Mononuclear phagocytes in tissue: from inflammation to cancer

Mononuclear phagocytes in tissue: from inflammation to cancer

Egle Kvedaraite
24 May
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Flow cytometric assays for CAR T cell manufacturing and post-infusion monitoring

Flow cytometric assays for CAR T cell manufacturing and post-infusion monitoring

Stephan Wilmes
23 May
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Exploring novel approaches for AAV analysis

Exploring novel approaches for AAV analysis

Roxana Eggleston-Rangel
18 May
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Cell profiling and biomarker discovery in a spatial context: a guide to analyzing your spatial biology data for immuno-oncology applications

Cell profiling and biomarker discovery in a spatial context: a guide to analyzing your spatial biology data for immuno-oncology applications

Telma Santos
17 May
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Enabling instrument connectivity through digital automation

Enabling instrument connectivity through digital automation

Bruce Greenwald, Elizabeth Wahl
11 May
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Spatial biology out of the box: a pre-defined antibody panel for TME phenotyping of solid tumors

Spatial biology out of the box: a pre-defined antibody panel for TME phenotyping of solid tumors

Amy Jablonski
10 May
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Commercializing cell and gene therapies: Navigating complex commercial readiness hurdles for a successful product launch

Commercializing cell and gene therapies: Navigating complex commercial readiness hurdles for a successful product launch

Andrea Briggs
9 May
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Manufacturing and testing a clinical-grade AAV vector: from concept to clinic

Manufacturing and testing a clinical-grade AAV vector: from concept to clinic

Chris Edwards, James Cody
4 May
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Customize cell culture reagents and drive sustainability in your development: Make media and buffers your competitive advantage

Customize cell culture reagents and drive sustainability in your development: Make media and buffers your competitive advantage

S Ghassemi, R O’Connor, A Nandi et al.
3 May
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Spatial biology at its best – a complete workflow solution to advance immuno-oncology

Spatial biology at its best – a complete workflow solution to advance immuno-oncology

Jenia Schlegel, Sara Rahmati
3 May
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Environmental monitoring: optimizing microbial control in cell and gene therapy workflows

Environmental monitoring: optimizing microbial control in cell and gene therapy workflows

Nico Chow
27 April
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High-throughput process & analytical platforms to accelerate gene therapy scale-up

High-throughput process & analytical platforms to accelerate gene therapy scale-up

P Starremans PhD, K Warrington PhD, N Jesuraj PhD
25 April
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Large-scale genome editing of primary human natural killer (NK) cells: A quest toward manufacture of clinically relevant CAR NK cells

Large-scale genome editing of primary human natural killer (NK) cells: A quest toward manufacture of clinically relevant CAR NK cells

Deepak Kumar
20 April
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Analyzing full and empty AAV capsid ratio in less than 5 minutes

Analyzing full and empty AAV capsid ratio in less than 5 minutes

Åsa Hagner-McWhirter PhD
19 April
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Development of anti-AAV assay for detection of pre-existing AAV immunity

Development of anti-AAV assay for detection of pre-existing AAV immunity

Zhe Liu, John Chappell
18 April
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Navigating bottlenecks in cell therapy manufacturing: A versatile and scalable platform solution

Navigating bottlenecks in cell therapy manufacturing: A versatile and scalable platform solution

Peter Yates
13 April
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Skip the hassle for AAV and AdV empty/full and titer data with Stunner

Skip the hassle for AAV and AdV empty/full and titer data with Stunner

Nelis Denys
12 April
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Large-scale production of hiPSCs in automated bioreactors to produce wholly-cellular bioinks for tissue engineering

Large-scale production of hiPSCs in automated bioreactors to produce wholly-cellular bioinks for tissue engineering

Mark Skylar-Scott, Debbie Lee Lian Ho
12 April
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De-risking lentiviral vector production using a robust, scalable, suspension-based platform

De-risking lentiviral vector production using a robust, scalable, suspension-based platform

Jimmy Xin, Poornima Manavalan
11 April
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Cell therapy manufacturing and 21 CFR Part 11 compliance: Overview and considerations for instrument software

Cell therapy manufacturing and 21 CFR Part 11 compliance: Overview and considerations for instrument software

Ashley Smith, Brianna Volk
6 April
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Chromatographic modalities, buffer selection and other considerations for enrichment of AAV product

Chromatographic modalities, buffer selection and other considerations for enrichment of AAV product

Rok Žigon
5 April
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Overcoming challenges to succeed when transitioning into a cGMP environment

Overcoming challenges to succeed when transitioning into a cGMP environment

Kris Wronski
30 March
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Achieving reliable and scalable lentiviral vector production

Achieving reliable and scalable lentiviral vector production

Roy Liu
30 March
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A platform approach to tackling AAV potency

A platform approach to tackling AAV potency

Aisleen McColl-Carboni
30 March
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Scale-up and deliver allogeneic cell therapies to large patient populations

Scale-up and deliver allogeneic cell therapies to large patient populations

M Langtry, K Panchalingam, I Friedrich Ben-Nun
29 March
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Scalable production in single-use bioreactors

Scalable production in single-use bioreactors

Jonathan Zmuda PhD, Premkumar Jayaraman PhD
29 March
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Emerging trends and challenges in AAV manufacturing for gene therapies

Emerging trends and challenges in AAV manufacturing for gene therapies

M Fuller, A Eastham, I (John) Eugenis
28 March
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Next-generation CRISPR mRNA-LNPs and scale up manufacturing for CAR T cells

Next-generation CRISPR mRNA-LNPs and scale up manufacturing for CAR T cells

Reka Geczy, Bernice Thommandru
23 March
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Navigating evolving regulatory CMC guidance in the AAV gene therapy field

Navigating evolving regulatory CMC guidance in the AAV gene therapy field

Y Zhi, C Le Bec, M Brewer et al.
22 March
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Improve your speed to therapy and drive efficiency by integrating supply chain and manufacturing

Improve your speed to therapy and drive efficiency by integrating supply chain and manufacturing

Robert Lutskus, Matthew Lakelin
21 March
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Enabling rapid vaccine development through manufacturing innovation and process efficiency

Enabling rapid vaccine development through manufacturing innovation and process efficiency

C Kontoravdi, M Muralidhara, S Sikka et al.
15 March
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Case studies: Successful scale-up of upstream viral vector processes using adherent and suspension platforms

Case studies: Successful scale-up of upstream viral vector processes using adherent and suspension platforms

Samir Acharya, Denis Kole
14 March
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Pain points to potential: Positioning process and analytical development for next-gen cell therapies

Pain points to potential: Positioning process and analytical development for next-gen cell therapies

Sarah Campion, Alex Sargent
9 March
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Enabling and advancing mRNA-LNP medicines from concept to clinic

Enabling and advancing mRNA-LNP medicines from concept to clinic

L Jeffs, A Crowe, J Singh
8 March
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Advancing the purification of VSV-G pseudotyped lentiviral vectors by using affinity chromatography

Advancing the purification of VSV-G pseudotyped lentiviral vectors by using affinity chromatography

Pim Hermans, Frank Detmers
7 March
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Accelerating your AAV pathway to GMP and clinic

Accelerating your AAV pathway to GMP and clinic

James J Cody
6 March
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Patient-derived organoids: an emerging platform to de-risk immunotherapy development

Patient-derived organoids: an emerging platform to de-risk immunotherapy development

Sylvia F Boj, Andrea Bisso
2 March
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The fast and the curious – optimized development of high performing AAV vectors

The fast and the curious – optimized development of high performing AAV vectors

Dirk Grimm, David Schaffer
2 March
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Optimize your mRNA process from pDNA template to LNP encapsulation

Optimize your mRNA process from pDNA template to LNP encapsulation

Blaž Bakalar PhD
1 March
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Understanding donor characteristics to improve allogeneic cell therapy outcomes for all

Understanding donor characteristics to improve allogeneic cell therapy outcomes for all

A Madbouly, M Maiers, S Sullivan
28 February
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Driving the expansion of mRNA into the therapeutic sphere

Driving the expansion of mRNA into the therapeutic sphere

A Becerra, A Kuhn, M Kurtoglu
23 February
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Building an AAV platform in 2023: challenges, threats & opportunities

Building an AAV platform in 2023: challenges, threats & opportunities

Quentin Bazot, Mégane Denu
21 February
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Development of lentiviral vector packaging and producer cell lines

Development of lentiviral vector packaging and producer cell lines

Matthew Tridgett PhD
16 February
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Implementing a closed cell therapy manufacturing process through strategic collaboration

Implementing a closed cell therapy manufacturing process through strategic collaboration

X de Mollerat du Jeu PhD, Ø Åmellem PhD, B Shy MD PhD
14 February
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Eliminate hurdles of AAV purity assessment with capillary electrophoresis

Eliminate hurdles of AAV purity assessment with capillary electrophoresis

Chris Heger
9 February
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Ensure first-time right GMP production of gene therapies: Proven strategies for pre-clinical manufacturing and early process development

Ensure first-time right GMP production of gene therapies: Proven strategies for pre-clinical manufacturing and early process development

Avi Nandi, Tatiana Nanda PhD
2 February
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Challenges of developing ADA and concentration (PK or PD) assays for lysosomal transgene enzymes on an automated immunoassay platform

Challenges of developing ADA and concentration (PK or PD) assays for lysosomal transgene enzymes on an automated immunoassay platform

Issa Jyamubandi, John Chappell
26 January
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Sustainable plasmid DNA strategies: achieving streamlined, secured supply to clinic and commercialization

Sustainable plasmid DNA strategies: achieving streamlined, secured supply to clinic and commercialization

Andrew Frazer, Amanda Weiss
24 January
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Validating a rapid analytical method for DNA purity determination and platform harmonization

Validating a rapid analytical method for DNA purity determination and platform harmonization

Joe Ferraiolo
19 January
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Assessing efficacy and MoA of mono and combo immunotherapies in preclinical humanized models

Assessing efficacy and MoA of mono and combo immunotherapies in preclinical humanized models

K Thiam PhD, E van der Horst PhD, A Surya PhD
18 January
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Achieving robust fit-for-purpose analytical workflows that streamline cell and gene therapy development

Achieving robust fit-for-purpose analytical workflows that streamline cell and gene therapy development

Ioannis (John) Eugenis
17 January
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Optimizing HEK293 media for improved titers and VG/Capsid ratios

Optimizing HEK293 media for improved titers and VG/Capsid ratios

Hamid Soleymani
14 December 2022
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GMP-compliant manufacturing in a closed-system automated bioreactor with a novel cell culture medium

GMP-compliant manufacturing in a closed-system automated bioreactor with a novel cell culture medium

Gonçalo Regalo, Francesco Vitrani
13 December 2022
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Enhancing non-viral genome editing, processing, and expansion of T and NK cells

Enhancing non-viral genome editing, processing, and expansion of T and NK cells

Sung Lee, Deepak Kumar
8 December 2022
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The CAR toolkit: progress and challenges in CAR T/NK cell R&D and manufacture

The CAR toolkit: progress and challenges in CAR T/NK cell R&D and manufacture

H Dhamne, T Manning, S Steiner
7 December 2022
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How to secure and standardize your cell expansion

How to secure and standardize your cell expansion

Anette Brass, Paula Villaescusa Sánchez
6 December 2022
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Extracellular Vesicles: From Waste EVictees to Therapeutic Reality

Extracellular Vesicles: From Waste EVictees to Therapeutic Reality

Amy Kauffman
30 November 2022
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Simplifying lentiviral downstream processing with a novel affinity resin and robust analytical tools

Simplifying lentiviral downstream processing with a novel affinity resin and robust analytical tools

Chantelle Gaskin, Suzy Brown
29 November 2022
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Let the cells thrive - The next generation of cell expansion

Let the cells thrive - The next generation of cell expansion

H Fabre, M Barbisin, M Knaub
22 November 2022
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Scalable AAV production in single use bioreactors

Scalable AAV production in single use bioreactors

Jon Zmuda
21 November 2022
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Industrialization of cell and gene therapies: process development best practices for commercialization readiness

Industrialization of cell and gene therapies: process development best practices for commercialization readiness

Behnam Ahmadian Baghbaderani
17 November 2022
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Improved lentivirus recovery by weak anion exchange capture

Improved lentivirus recovery by weak anion exchange capture

Lisa Marx PhD
15 November 2022
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Viral vector manufacturing process - addressing bottlenecks with innovative solutions

Viral vector manufacturing process - addressing bottlenecks with innovative solutions

Rachel Legmann
8 November 2022
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How are cationic lipids offering new possibilities in the delivery of RNA therapeutics?

How are cationic lipids offering new possibilities in the delivery of RNA therapeutics?

Malik Hellal, Maria Nicla Loviglio
3 November 2022
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Navigating scalability and consistency in the allogeneic supply chain

Navigating scalability and consistency in the allogeneic supply chain

Anne Dircks, Dean Lee MD PhD
1 November 2022
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Tailoring viral vector transgene optimization for enhanced efficacy

Tailoring viral vector transgene optimization for enhanced efficacy

Harrison Brown
27 October 2022
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Modulation of both tumor and T cell apoptosis to enhance CART immunotherapy

Modulation of both tumor and T cell apoptosis to enhance CART immunotherapy

Marco Ruella
26 October 2022
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Lentiviral titer determination: Rapid and robust molecular methods suitable for validation

Lentiviral titer determination: Rapid and robust molecular methods suitable for validation

Unnati Dev
25 October 2022
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Regulatory requirements and product attributes for cGMP viral vector production

Regulatory requirements and product attributes for cGMP viral vector production

Scott Cross, Shikha Mishra
20 October 2022
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Circulating tumor DNA as a predictive biomarker for immunotherapy response: from clinical trials to clinical practice

Circulating tumor DNA as a predictive biomarker for immunotherapy response: from clinical trials to clinical practice

M Krainock, A Tan, J Simmons
19 October 2022
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Manufacturing GMP-compliant iPSCs in closed and open systems

Manufacturing GMP-compliant iPSCs in closed and open systems

Dhruv Sareen, Chao Sheng
18 October 2022
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Scalable suspension lentiviral vector production platforms for cGMP manufacturing

Scalable suspension lentiviral vector production platforms for cGMP manufacturing

Suparna Sanyal PhD
13 October 2022
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Predicting patient response to immune targeted therapies via interrogation of the TME

Predicting patient response to immune targeted therapies via interrogation of the TME

Mark Uhlik PhD, Caroline Fong MD
12 October 2022
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The next generation of GMP cell sorting - high-throughput, sterile, scalable

The next generation of GMP cell sorting - high-throughput, sterile, scalable

Samson Rogers PhD
11 October 2022
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Process development optimization for GMP manufacturing: A CAR-T case study

Process development optimization for GMP manufacturing: A CAR-T case study

Gary Pigeau PhD
6 October 2022
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Automating HSC gene engineering in a functionally closed system

Automating HSC gene engineering in a functionally closed system

L Stamm, K Krämer, E Papanikolaou
4 October 2022
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Feeder free expansion and closed wash and concentration of a clinically relevant number of human NK cells

Feeder free expansion and closed wash and concentration of a clinically relevant number of human NK cells

Erica Heipertz PhD
29 September 2022
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Process and analytical insights for GMP manufacturing of mRNA lipid nanoparticles

Process and analytical insights for GMP manufacturing of mRNA lipid nanoparticles

E Cameau, P Zhang, S Ip et al.
28 September 2022
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Manufacturing of NK cells for the clinic: the Spanish experience

Manufacturing of NK cells for the clinic: the Spanish experience

A Pérez-Martínez PhD, M Giedlin PhD, M L Ammari PhD
27 September 2022
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Overcoming contamination risks in cell and gene therapy with aseptic GMP process design using isolator technology

Overcoming contamination risks in cell and gene therapy with aseptic GMP process design using isolator technology

Chris Berridge, Donald Singer
22 September 2022
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Accelerating immuno-oncology innovation using humanized mouse models

Accelerating immuno-oncology innovation using humanized mouse models

Santi Suryani Chen PhD
21 September 2022
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Addressing current challenges in lentiviral vector purification and associated analytics

Addressing current challenges in lentiviral vector purification and associated analytics

Bryan Zee, Anindya Dasgupta
20 September 2022
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Scaling up an AAV production platform to support clinical and commercial needs: challenges and opportunities

Scaling up an AAV production platform to support clinical and commercial needs: challenges and opportunities

I Iwuchukwu, T Cunningham, A Becerra
20 September 2022
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Overcoming quality and regulatory challenges to reliably take your cell & gene therapy to commercialization

Overcoming quality and regulatory challenges to reliably take your cell & gene therapy to commercialization

Andreas Wirth, Christoph Meyer
15 September 2022
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Achieve significantly increased adenovirus yield with density gradient ultracentrifugation: a comparative study

Achieve significantly increased adenovirus yield with density gradient ultracentrifugation: a comparative study

Shawn Sternisha PhD
13 September 2022
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Successful workflows for GMP-compliant cell manufacturing & analytics

Successful workflows for GMP-compliant cell manufacturing & analytics

A Steinbach, A Manser, H Adoni
8 September 2022
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Round table discussion: Successful suspension-based viral vector manufacturing scale-up, from process development to clinics

Round table discussion: Successful suspension-based viral vector manufacturing scale-up, from process development to clinics

D Kole, L Giannunzio BS, C Peigné et al.
7 September 2022
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Complete system for AAV production for clinical production: Part 1 Upstream

Complete system for AAV production for clinical production: Part 1 Upstream

Jenny England PhD, Jonathan Zmuda PhD
2 September 2022
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Smart and scalable transfection platforms for start-to-finish AAV and LV development

Smart and scalable transfection platforms for start-to-finish AAV and LV development

Leisha Kopp
1 September 2022
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Automated and scalable closed-system platform for cell isolation and activation

Automated and scalable closed-system platform for cell isolation and activation

Hany Meås
31 August 2022
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International differences in cellular starting material quality and regulatory requirements

International differences in cellular starting material quality and regulatory requirements

B Kuker, P Machalik, S Ahmed et al.
30 August 2022
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Optimizing vector production and purification to enhance scalable AAV manufacturing

Optimizing vector production and purification to enhance scalable AAV manufacturing

Chantelle Gaskin, Jon Zmuda PhD
25 August 2022
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Overcoming challenges in transitioning stem cell expansion from the laboratory to commercial production

Overcoming challenges in transitioning stem cell expansion from the laboratory to commercial production

Ben Josey PhD
23 August 2022
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Emphasizing flows and functions – How intuitive design can enhance the functionality of an ATMP manufacturing facility

Emphasizing flows and functions – How intuitive design can enhance the functionality of an ATMP manufacturing facility

Shany Albalak Assoc AIA, Jan Bondoc AIA LEED GA
16 August 2022
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Forward engineering cell therapy production capabilities to save patient lives

Forward engineering cell therapy production capabilities to save patient lives

John Lee PhD
11 August 2022
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Case Study: Streamlining AAV titer determination using variable pathlength technology

Case Study: Streamlining AAV titer determination using variable pathlength technology

Yan Chen PhD, Joseph Ferraiolo
10 August 2022
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High throughput viral titering of AAV throughout the production continuum

High throughput viral titering of AAV throughout the production continuum

Kelly Geosits
4 August 2022
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Optimizing cell proliferation and function for immunotherapy with recombinant growth factors & cytokines

Optimizing cell proliferation and function for immunotherapy with recombinant growth factors & cytokines

Martin P Keough PhD
3 August 2022
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Build vs buy dilemma: economics of manufacturing cell-based therapies

Build vs buy dilemma: economics of manufacturing cell-based therapies

Nirupama (Rupa) Pike
28 July 2022
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Optimizing and standardizing the cryopreservation of cellular samples: new data and insights from the UK’s Advanced Therapy Treatment Centres program

Optimizing and standardizing the cryopreservation of cellular samples: new data and insights from the UK’s Advanced Therapy Treatment Centres program

Julie Meneghel, Sandeep Kumar
21 July 2022
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Mycoplasma testing regulatory guidance and strategies for cGMP cell and gene therapy manufacturing

Mycoplasma testing regulatory guidance and strategies for cGMP cell and gene therapy manufacturing

Michael Brewer
19 July 2022
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Scalability considerations when using cord blood as an allogeneic starting material

Scalability considerations when using cord blood as an allogeneic starting material

J Aho PhD, W van’t Hof PhD, A Kaestner
14 July 2022
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Adapting the power of density gradient separations for characterizing viral vector fullness

Adapting the power of density gradient separations for characterizing viral vector fullness

Shawn Sternisha PhD
12 July 2022
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Autologous cell therapies - the path to commercial viability

Autologous cell therapies - the path to commercial viability

Joe Garrity
7 July 2022
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Transient expression of mRNA lipid nanoparticle-based chimeric antigen receptors for safe immunotherapy

Transient expression of mRNA lipid nanoparticle-based chimeric antigen receptors for safe immunotherapy

Sandy Tretbar
6 July 2022
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Feasibility of a Fixed Bed Bioreactor for Expansion of hESCs

Feasibility of a Fixed Bed Bioreactor for Expansion of hESCs

Hannah Rasby
30 June 2022
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Thinking translational: Things to consider in CAR T cell research workflows

Thinking translational: Things to consider in CAR T cell research workflows

Saskia Rösch PhD
22 June 2022
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Transfection innovation for large scale AAV and LV – Considerations for process development through commercial manufacturing

Transfection innovation for large scale AAV and LV – Considerations for process development through commercial manufacturing

Geddy Hamblen
21 June 2022
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Accelerating cell therapy discovery & development with non-viral gene engineering

Accelerating cell therapy discovery & development with non-viral gene engineering

D Hermanson, X Patrinostro, S Silaika
16 June 2022
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Overcoming current challenges in immunotherapy drug development with patient-derived organoids

Overcoming current challenges in immunotherapy drug development with patient-derived organoids

Sylvia F Boj
15 June 2022
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Optimizing mRNA purification conditions by using a High Throughput Screening approach

Optimizing mRNA purification conditions by using a High Throughput Screening approach

Jenny England
14 June 2022
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Taking a right first-time approach to optimize end-to-end viral vector manufacturing

Taking a right first-time approach to optimize end-to-end viral vector manufacturing

Hanna Lesch, Julien Depollier
9 June 2022
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Life on a chip - vascularized micro-tumor chips for mimicking clinical drug responses

Life on a chip - vascularized micro-tumor chips for mimicking clinical drug responses

Chris Hughes
8 June 2022
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Applying an HPLC analytical platform for mRNA process monitoring

Applying an HPLC analytical platform for mRNA process monitoring

Nejc Pavlin
7 June 2022
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Optimizing E. Coli cell growth performance with in-line, real-time OD600 (abs/mm) monitoring during the fermentation process

Optimizing E. Coli cell growth performance with in-line, real-time OD600 (abs/mm) monitoring during the fermentation process

Tanja Buch, Ramsey Shanbaky
1 June 2022
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Monitoring of circulating CAR T cells

Monitoring of circulating CAR T cells

A Graband, S Hünecke, M Bremm
31 May 2022
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Improving T cell therapy manufacturing processes with automation and scalability

Improving T cell therapy manufacturing processes with automation and scalability

Evan Zynda PhD
26 May 2022
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Streamlined workflow solutions for cell and gene therapy analytics

Streamlined workflow solutions for cell and gene therapy analytics

Annika Graband
24 May 2022
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Strategic partnering to enable cell therapy commercialization

Strategic partnering to enable cell therapy commercialization

Jenessa Smith, Xavier de Mollerat du Jeu
12 May 2022
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Manufacturing considerations for viral and non-viral platform selection

Manufacturing considerations for viral and non-viral platform selection

V Slepushkin , A Noyes, A Hagerman et al.
10 May 2022
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Process development excellence to de-risk and accelerate commercialization of cell and gene therapies

Process development excellence to de-risk and accelerate commercialization of cell and gene therapies

Behnam Ahmadian Baghbaderani
5 May 2022
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From cells to purified capsids: How to develop a scalable rAAV process

From cells to purified capsids: How to develop a scalable rAAV process

Åsa Hagner McWhirter
3 May 2022
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Strategic supply chain design: flexibility and scalability considerations for optimal facility design

Strategic supply chain design: flexibility and scalability considerations for optimal facility design

Niranjan Kulkarni PhD, Grace Linton RA AIA LEED AP BD+C
28 April 2022
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Removing technological barriers to efficient large-scale LV vector production

Removing technological barriers to efficient large-scale LV vector production

R Lopez de Maturana, E Jackson-Holmes, M Neri et al.
26 April 2022
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Process development innovations to improve gene therapy manufacturing

Process development innovations to improve gene therapy manufacturing

Jessica Hilmoe, Michael Shen
21 April 2022
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Automating cell manufacturing: customized solutions for research, development and industry

Automating cell manufacturing: customized solutions for research, development and industry

Marko Gogala
20 April 2022
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Applications and benefits of the CTS Rotea Counterflow Centrifugation System in cell therapy workflows

Applications and benefits of the CTS Rotea Counterflow Centrifugation System in cell therapy workflows

Carl Dargitz
13 April 2022
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Increasing productivity of IVT reaction using at-line monitoring by HPLC chromatography

Increasing productivity of IVT reaction using at-line monitoring by HPLC chromatography

Rok Sekirnik
12 April 2022
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Supply chain efficiency and sourcing for scaling your gene therapy operation

Supply chain efficiency and sourcing for scaling your gene therapy operation

Celine Martin, Don Young
7 April 2022
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Discovery to manufacturing: A continuum

Discovery to manufacturing: A continuum

A Chang, T Hitchcock, B Fry
5 April 2022
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Scaling non-viral cell therapy approaches for solid tumour treatments

Scaling non-viral cell therapy approaches for solid tumour treatments

N Andronikou, E Zynda PhD, K Jacoby PhD
31 March 2022
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A scalable lentiviral vector production system based on stable producer cell lines

A scalable lentiviral vector production system based on stable producer cell lines

Roy Bin Liu
29 March 2022
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Scaling non-viral cell therapy approaches for solid tumor treatments

Scaling non-viral cell therapy approaches for solid tumor treatments

N Andronikou, E Zynda PhD, K Jacoby PhD
24 March 2022
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What does Plug-and-Play offer large-scale AAV manufacturing?

What does Plug-and-Play offer large-scale AAV manufacturing?

Margherita Neri, Claire Wartel-Weill
22 March 2022
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Flexible and scalable solutions for AAV viral vector production using a templated platform

Flexible and scalable solutions for AAV viral vector production using a templated platform

Eva Fong
17 March 2022
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Automated GMP-compliant PSC banking in a closed system

Automated GMP-compliant PSC banking in a closed system

Chao Sheng PhD, Rafal Krol PhD
15 March 2022
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Rapid translation of a cellular therapeutic: Choosing product & process development solutions for clinical manufacturing readiness

Rapid translation of a cellular therapeutic: Choosing product & process development solutions for clinical manufacturing readiness

Ashish Patel, Joseph Candiello
10 March 2022
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Accelerate your cell and gene therapy workflows with next-generation analytical tools

Accelerate your cell and gene therapy workflows with next-generation analytical tools

Chris Heger
8 March 2022
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Simplifying analytical development for viral vector production: robust and sensitive methods for common expression systems

Simplifying analytical development for viral vector production: robust and sensitive methods for common expression systems

Srinath Kashi Ranganath
3 March 2022
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Rethink CAR T cell therapy with a scalable RNA lipid nanoparticle platform

Rethink CAR T cell therapy with a scalable RNA lipid nanoparticle platform

Angela Zhang PhD, Reka Geczy PhD
1 March 2022
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Introducing Lonza’s AAV suspension transient transfection platform to de-risk your path to clinic

Introducing Lonza’s AAV suspension transient transfection platform to de-risk your path to clinic

Suparna Sanyal
24 February 2022
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Manufacturing of RCA-free adenoviral vectors

Manufacturing of RCA-free adenoviral vectors

Nico Scheer
22 February 2022
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AAV manufacturing process development using fast USP and DSP HPLC analytics

AAV manufacturing process development using fast USP and DSP HPLC analytics

Aleš Štrancar
17 February 2022
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How to monitor protein impurities to ensure consistent cell and gene therapy products

How to monitor protein impurities to ensure consistent cell and gene therapy products

Ejvind Mørtz
15 February 2022
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TESSA technology: A new era for AAV manufacture

TESSA technology: A new era for AAV manufacture

Ryan Cawood
10 February 2022
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Exploring the charge heterogeneity in recombinant adeno-associated virus with imaged isoelectric focusing

Exploring the charge heterogeneity in recombinant adeno-associated virus with imaged isoelectric focusing

Julie Wei
8 February 2022
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The digital revolution: Technological innovations to enable automation in cell therapy manufacturing

The digital revolution: Technological innovations to enable automation in cell therapy manufacturing

S Chang, B Greenwald, K Roy
3 February 2022
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Accelerate process development with at-line concentration measurement

Accelerate process development with at-line concentration measurement

Joseph Ferraiolo
1 February 2022
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Professionalizing mesenchymal stem cells for therapeutic benefit

Professionalizing mesenchymal stem cells for therapeutic benefit

Anthony Ting PhD
20 January 2022
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Accelerating gene therapy development: from concept to clinic

Accelerating gene therapy development: from concept to clinic

S Gill, Q Liu, R Cawood
20 January 2022
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Abeona Therapeutics Evaluates a Scalable Suspension-based Platform for Production of Viral Vector for MPS-IIIA

Abeona Therapeutics Evaluates a Scalable Suspension-based Platform for Production of Viral Vector for MPS-IIIA

Phillip B Maples PhD, Anne MacIntyre
18 January 2022
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Cell and gene therapy matures: Streamlining and smoothing the path to commercialization

Cell and gene therapy matures: Streamlining and smoothing the path to commercialization

Matt Hewitt PhD
11 January 2022
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Automating the final cell therapy bioprocess step for robust CMC/GMP compliance

Automating the final cell therapy bioprocess step for robust CMC/GMP compliance

Tracy Moore, Delara Motlagh
11 January 2022
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Current technological trends and advancements in vector purification

Current technological trends and advancements in vector purification

C Gaskin, A Saksule, N Clement PhD et al.
15 December 2021
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Putting the patient first: New modalities of manufacturing for cell therapy through real-time process changes

Putting the patient first: New modalities of manufacturing for cell therapy through real-time process changes

C C White III, B Wang, K Wang
9 December 2021
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Developing stem cell therapies: expansion strategies and lessons learned

Developing stem cell therapies: expansion strategies and lessons learned

S Mei PhD MSc, L McIntyre MD MHSc FRCPC, C Siler PhD
8 December 2021
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Accelerating Plasmid Production by Optimizing Your Process Analytics

Accelerating Plasmid Production by Optimizing Your Process Analytics

Paul Mania
2 December 2021
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Enabling clinical grade manufacturing of gene-engineered NK cells

Enabling clinical grade manufacturing of gene-engineered NK cells

N Möker, E Ullrich MD, R Romee MD et al.
30 November 2021
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Magnetic selection for consistent cellular starting material in autologous cell therapy manufacture

Magnetic selection for consistent cellular starting material in autologous cell therapy manufacture

Kenneth Olsen PhD, Rachel Perret PhD
23 November 2021
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Achieving high non-viral transfection performance for cell therapy processing

Achieving high non-viral transfection performance for cell therapy processing

N Andronikou, T Roth PhD MD, J Fraietta
16 November 2021
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Advancing engineered cell and gene therapy with precision gene editing

Advancing engineered cell and gene therapy with precision gene editing

Danilo Maddalo PhD, John Lambourne PhD
11 November 2021
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Automated cell expansion: Current technologies and trends

Automated cell expansion: Current technologies and trends

D Sethi PhD, A Kilgore PhD, K Schneider
9 November 2021
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Considerations for developing scalable and efficient collection network processes

Considerations for developing scalable and efficient collection network processes

L Anderson, S Butler, A Montalvo
28 October 2021
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Platform optimization for efficient AAV purification – insights from a CDMO

Platform optimization for efficient AAV purification – insights from a CDMO

Nicolas Laroudie, Vincent Ravault
26 October 2021
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Optimization of AAV production for high-yielding and scalable GMP processes

Optimization of AAV production for high-yielding and scalable GMP processes

C Wartel-Weill PhD, M Porte, B Kondragunta PhD et al.
20 October 2021
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cGMP manufacturing made easy – a case study by ElevateBio

cGMP manufacturing made easy – a case study by ElevateBio

Michael Paglia, Shannon Eaker
14 October 2021
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Gain deeper insights into the mechanisms of immune cell killing of tumor cells: accelerate your time to answer with integrated software analysis

Gain deeper insights into the mechanisms of immune cell killing of tumor cells: accelerate your time to answer with integrated software analysis

C Souders PhD, T Dale PhD, N Bevan et al.
6 October 2021
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The therapeutic gene editing solution – cell therapy for solid tumors

The therapeutic gene editing solution – cell therapy for solid tumors

B Sasu PhD, P Sivakumar PhD, J Trager PhD et al.
30 September 2021
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GMP manufacturing for exosome-based therapies: the critical role of analytics and process design for clinical production and scale-up

GMP manufacturing for exosome-based therapies: the critical role of analytics and process design for clinical production and scale-up

Marcos Langtry, Davide Zocco
28 September 2021
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Get your non-viral T cell engineering process ready for clinical manufacturing

Get your non-viral T cell engineering process ready for clinical manufacturing

M Rietenbach, S Wild, K Patel
21 September 2021
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AAV manufacturing with stable producer cells for industrial scale vector production

AAV manufacturing with stable producer cells for industrial scale vector production

Ben Hudjetz
16 September 2021
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Scalable, flexible manufacture: simplifying cell & gene therapy production

Scalable, flexible manufacture: simplifying cell & gene therapy production

J Bornholdt AIA PE LEED AP, N Kulkarni PhD, C Houts
8 September 2021
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The setup and payoff: entering the clinic and the market efficiently by leveraging a platform lentiviral vector process

The setup and payoff: entering the clinic and the market efficiently by leveraging a platform lentiviral vector process

Kevin D Beck PhD
1 September 2021
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Are you finishing strong in cell therapy manufacturing? Tackling your final fill and finish challenges with automation.

Are you finishing strong in cell therapy manufacturing? Tackling your final fill and finish challenges with automation.

Dalip Sethi, Annie Cunningham
31 August 2021
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Midstream unit operations: Unsung heroes in AAV process development

Midstream unit operations: Unsung heroes in AAV process development

Matthew Roach, Ratish Krishnan
18 August 2021
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Cell-based therapies for cancer treatment: leveraging advanced flow cytometry for greater clinical insight

Cell-based therapies for cancer treatment: leveraging advanced flow cytometry for greater clinical insight

N Senutovitch PhD, R Fan PhD, T J Laskowski PhD
5 August 2021
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Optimizing downstream purification of high-quality plasmid DNA for gene therapy and vaccine production

Optimizing downstream purification of high-quality plasmid DNA for gene therapy and vaccine production

Alejandro Becerra, Johannes F Buyel
3 August 2021
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Accelerating CAR-T process development: The power of process insight

Accelerating CAR-T process development: The power of process insight

Julia Hupfeld PhD
29 July 2021
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Expression systems for viral vector production: advantages of the Sf9 Baculovirus system and simple solutions to address its specific analytical challenges

Expression systems for viral vector production: advantages of the Sf9 Baculovirus system and simple solutions to address its specific analytical challenges

Yi Fang Lee, Srinath Kashi Ranganath
22 July 2021
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Assuring manufacturing and data integrity for cell and gene therapy regulatory compliance

Assuring manufacturing and data integrity for cell and gene therapy regulatory compliance

Jelena Jurlin, Dmitry Fridman
14 July 2021
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Delivering an end-to-end industrialization roadmap for autologous cell therapy

Delivering an end-to-end industrialization roadmap for autologous cell therapy

M Hewitt PhD, J Garrity, W Bagni
6 July 2021
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Applying a closed, modular, semi-automated system to CAR T cell therapy manufacturing

Applying a closed, modular, semi-automated system to CAR T cell therapy manufacturing

Y Ji PhD, S Ensari PhD, N Moore PhD
29 June 2021
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Addressing the challenges of purification & quality control in gene therapy

Addressing the challenges of purification & quality control in gene therapy

A Bhattacharya PhD, L Kopp, K Richter PhD et al.
24 June 2021
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Strategies to advance the donor selection process for cell therapies to improve outcomes

Strategies to advance the donor selection process for cell therapies to improve outcomes

M Maiers, P Effie Wang Petersdorf, K Wadsworth et al.
17 June 2021
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Overcoming purification challenges in antibody therapeutics manufacturing with subdomain-specific affinity solutions

Overcoming purification challenges in antibody therapeutics manufacturing with subdomain-specific affinity solutions

Laurens Sierkstra
10 June 2021
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Key considerations for maximizing LV and AAV production in transient transfection workflows

Key considerations for maximizing LV and AAV production in transient transfection workflows

L Kopp, B Larimore, A Dasgupta et al.
9 June 2021
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Navigating regulations - novel cell therapy platforms and their path to clinical manufacturing

Navigating regulations - novel cell therapy platforms and their path to clinical manufacturing

N Bauer, N Calhoun, A Davies et al.
27 May 2021
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Protein biomarkers in plasma: revealing biological insights into the tumor microenvironment

Protein biomarkers in plasma: revealing biological insights into the tumor microenvironment

Genevieve Boland, Arnav Mehta
20 May 2021
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Improving upon legacy vector and plasmid bioprocess technology for tomorrow’s advanced therapies

Improving upon legacy vector and plasmid bioprocess technology for tomorrow’s advanced therapies

M Lundgren, P Guterstam, H Ihre
18 May 2021
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Applying Warp Speed lessons to your ATMP manufacturing facility

Applying Warp Speed lessons to your ATMP manufacturing facility

J P Bornholdt, C Heffernan, T Page et al.
12 May 2021
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From first collection to commercial launch: Streamlining your supply chain to support next generation therapies

From first collection to commercial launch: Streamlining your supply chain to support next generation therapies

Chris McClain, Aileen Baquiran
6 May 2021
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Key considerations for hMSC product and process development through clinical cGMP manufacturing

Key considerations for hMSC product and process development through clinical cGMP manufacturing

J Rowley, R Barcia, J Candiello et al.
28 April 2021
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Key lessons for cell & gene therapy and mRNA therapeutic development from COVID-19 mRNA vaccine approvals

Key lessons for cell & gene therapy and mRNA therapeutic development from COVID-19 mRNA vaccine approvals

S Zobbi, V Indurthi PhD, C Kröner et al.
22 April 2021
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Ultrahigh-content imaging helps to identify CAR target candidates against pancreatic adenocarcinoma

Ultrahigh-content imaging helps to identify CAR target candidates against pancreatic adenocarcinoma

Daniel Schäfer
20 April 2021
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Scalable suspension LVV production platforms for cell and gene therapy

Scalable suspension LVV production platforms for cell and gene therapy

S Sanyal, M Haller, Y Shin
13 April 2021
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Navigating current translational challenges in establishing clinical CAR T cell therapy manufacture

Navigating current translational challenges in establishing clinical CAR T cell therapy manufacture

E García Guerreiro, S Kassim, M Dudley et al.
7 April 2021
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How crucial is automation of fill and finish? Considerations to overcome challenges of the final formulation, fill and finish process.

How crucial is automation of fill and finish? Considerations to overcome challenges of the final formulation, fill and finish process.

Dalip Sethi
30 March 2021
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Studying solid tumors and their micro-environment based on automated large-scale 3D fluorescence imaging

Studying solid tumors and their micro-environment based on automated large-scale 3D fluorescence imaging

Nizar Yousif, Hussein Hamzeh
25 March 2021
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FectoVIR®-AAV, the new tool to enhance recombinant AAV production for gene therapy

FectoVIR®-AAV, the new tool to enhance recombinant AAV production for gene therapy

M Porte, E Da Silva Ferrada, V Lang
24 March 2021
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Harnessing the power of tumor-infiltrating lymphocytes for cell therapy

Harnessing the power of tumor-infiltrating lymphocytes for cell therapy

S Pelletier PhD, F Eppler PhD, N Monhasery PhD
3 March 2021
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Large-scale LVV production: from industry-leading process development to high quality GMP vector

Large-scale LVV production: from industry-leading process development to high quality GMP vector

G Vallanti, A Aiuti, M Sabatino
25 February 2021
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Exploring the capabilities of a versatile, novel, automated closed system for cell and gene therapy manufacturing

Exploring the capabilities of a versatile, novel, automated closed system for cell and gene therapy manufacturing

Premkumar Jayaraman PhD, Sarah Daoudi
16 February 2021
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Fitting product to process: raw materials customization for cell therapy manufacturing success

Fitting product to process: raw materials customization for cell therapy manufacturing success

J Paul Tomtishen III, L Clarke PhD, L Belcastro PhD et al.
11 February 2021
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Supporting development of mRNA-based therapies by addressing large scale purification challenges

Supporting development of mRNA-based therapies by addressing large scale purification challenges

Kelly Flook
9 February 2021
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Breaking barriers in viral vector titer analysis speed, volume, and data quality

Breaking barriers in viral vector titer analysis speed, volume, and data quality

R Durham PhD, J Stanta PhD, K Hanson PhD et al.
27 January 2021
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Focusing on donor characteristics and efficient selection to improve allogeneic cell therapy outcomes

Focusing on donor characteristics and efficient selection to improve allogeneic cell therapy outcomes

M Maiers MS, B Aftab PhD, D Gibson et al.
21 January 2021
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Case study: Optimization of lentiviral vector production from early stages to GMP

Case study: Optimization of lentiviral vector production from early stages to GMP

C Wartel-Weill PhD, N Elizalde PhD, R López de Maturana PhD
19 January 2021
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Raw materials of biological origin: navigating regulatory requirements for cell therapies

Raw materials of biological origin: navigating regulatory requirements for cell therapies

Marlin Frechette, Dominic Clarke
13 January 2021
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Streamlining CAR-T manufacture: reducing complexity and improving robustness through acoustic cell processing

Streamlining CAR-T manufacture: reducing complexity and improving robustness through acoustic cell processing

K Lannon, B Ross-Johnsrud, M Li et al.
9 December 2020
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The right time to move to an automated manufacturing system like the Cocoon platform: the when, the why, and the how

The right time to move to an automated manufacturing system like the Cocoon platform: the when, the why, and the how

Matthew Hewitt, Donna Rill
3 December 2020
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Innovative capillary electrophoresis techniques for gene therapy R&D

Innovative capillary electrophoresis techniques for gene therapy R&D

Chris Heger PhD, Julie Wei
1 December 2020
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Focus on allogeneic CAR-Ts manufacturing challenges and solutions

Focus on allogeneic CAR-Ts manufacturing challenges and solutions

M Langtry, A Sargent, B Ahmadian Baghbaderani
5 November 2020
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Scalable AAV manufacturing – Addressing challenges across the workflow

Scalable AAV manufacturing – Addressing challenges across the workflow

K Thompson, C Yan Liu, J Li et al.
29 October 2020
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Evolving the role of gene editing in cell therapy

Evolving the role of gene editing in cell therapy

J Frampton, T Thwaites, T Meissner
6 October 2020
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The multi-modal manufacturing movement - you don't need to know the future to be ready for it

The multi-modal manufacturing movement - you don't need to know the future to be ready for it

Peter Walters, Noel Maestre PE LEED AP
30 September 2020
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Scalable commercial manufacturing: a key strategic element for success of next generation exosome-based cell-free therapies

Scalable commercial manufacturing: a key strategic element for success of next generation exosome-based cell-free therapies

Behzad Mahdavi MBA PhD, Senthil Ramaswamy
24 September 2020
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Optimizing antibody discovery strategy for clinical success of next-gen immuno-oncology therapeutics

Optimizing antibody discovery strategy for clinical success of next-gen immuno-oncology therapeutics

P Ott MD PhD, I Roodink PhD, N Senutovitch PhD
23 September 2020
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Get your assay in gear – removing analytical bottlenecks on the path to clinical readiness

Get your assay in gear – removing analytical bottlenecks on the path to clinical readiness

Ian Gaudet
8 September 2020
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Identifying the critical factors for commercial-scale viral vector process development and manufacturing

Identifying the critical factors for commercial-scale viral vector process development and manufacturing

B Ahmadian Baghbaderani, X Swanson, S Sanyal
26 August 2020
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Realizing flexible automation – Closing gaps to meet industry needs

Realizing flexible automation – Closing gaps to meet industry needs

K Niss PhD, S Thompson PhD, M Lowdell PhD
12 August 2020
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Size matters: ensuring donor pool sustainability and cell therapy supply chain success when scaling up and out

Size matters: ensuring donor pool sustainability and cell therapy supply chain success when scaling up and out

C Learn PhD, A Agarwal, R Hornung MBA MBCI CEM CBCP
6 August 2020
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Scalable and efficient AAV production process with new Fibro chromatography technology

Scalable and efficient AAV production process with new Fibro chromatography technology

L Adamson-Small, M Lundgren, P Guterstam
30 July 2020
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Manufacturing of endogenous, non-engineered, antigen specific T cells against tumor targets

Manufacturing of endogenous, non-engineered, antigen specific T cells against tumor targets

Ali Mohamed, Megan Ciarlo
14 July 2020
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Challenges of cell collections for cell therapy manufacturing: what do we want in the bag?

Challenges of cell collections for cell therapy manufacturing: what do we want in the bag?

E Valdez RN MSN, J Beltzer, S Soni et al.
24 June 2020
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Simplifying GMP CAR-T and CAR NK cell therapy manufacturing processes

Simplifying GMP CAR-T and CAR NK cell therapy manufacturing processes

M Elia Luevano Salinas PhD, X Wang PhD, S Fricke PhD et al.
9 June 2020
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Enabling the industrialization of human induced pluripotent stem cell-based therapies

Enabling the industrialization of human induced pluripotent stem cell-based therapies

K Panchalingam, I Friedrich Ben-Nun, M Langtry
4 June 2020
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AAV downstream processing for industrial scale production – moving towards commercial manufacturing

AAV downstream processing for industrial scale production – moving towards commercial manufacturing

Orjana Terova, Mikhail Goldfarb
20 May 2020
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From vein to vein: how starting material quality impacts the manufacturing and success of next-generation therapies

From vein to vein: how starting material quality impacts the manufacturing and success of next-generation therapies

C McClain, M Giedlin, B Baghbaderani et al.
7 May 2020
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Stable AAV producer cell lines: elevating vector manufacturing

Stable AAV producer cell lines: elevating vector manufacturing

Silke Wissing
5 May 2020
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Advances in gene therapy delivery: next-generation transfection reagent for large-scale AAV manufacturing

Advances in gene therapy delivery: next-generation transfection reagent for large-scale AAV manufacturing

Mathieu Porte, Malik Hellal
29 April 2020
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Scaling up viral vector manufacturing with adherent and suspension cell cultures

Scaling up viral vector manufacturing with adherent and suspension cell cultures

C Glover, R Legmann, S Gupta
21 April 2020
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Lentiviral vector process to accelerate cell and gene therapy clinical development and commercialization

Lentiviral vector process to accelerate cell and gene therapy clinical development and commercialization

Kevin Beck
16 April 2020
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Enabling new cell therapies with GMP-compliant multiparametric cell sorting

Enabling new cell therapies with GMP-compliant multiparametric cell sorting

S Elliman, I Lai, S Pelletier et al.
18 March 2020
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Ensuring source material consistency and continuity for commercialization of advanced therapies

Ensuring source material consistency and continuity for commercialization of advanced therapies

D Clarke, A Shaw, C Good
12 March 2020
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Development and validation of quantitative real-time PCR for the detection of residual HEK-293 host cell DNA

Development and validation of quantitative real-time PCR for the detection of residual HEK-293 host cell DNA

Kara Norman
27 February 2020
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Multi-modal facilities: delivering flexible, future-proof ATMP manufacturing

Multi-modal facilities: delivering flexible, future-proof ATMP manufacturing

Emily Thompson, Noel Maestre
12 February 2020
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Scaling up and out: developing a commercial supply chain strategy to successfully deliver next-generation therapies

Scaling up and out: developing a commercial supply chain strategy to successfully deliver next-generation therapies

T Tripp, J Aho, P Niedzwiedz
6 February 2020
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Capsid titre quantification for AAV-based therapeutics

Capsid titre quantification for AAV-based therapeutics

John Chappell, Tomasz Witkos
30 January 2020
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Collaborative development of a new fill/finish instrument

Collaborative development of a new fill/finish instrument

A Schlinker, C Wegener, D Smith et al.
28 January 2020
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A pragmatic approach to the buy vs build manufacturing dilemma

A pragmatic approach to the buy vs build manufacturing dilemma

N Haderbache, C Houts, J Phillips
16 January 2020
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Combining state-of-the-art production, purification and analytics to optimize AAV manufacturing for clinical and commercial gene therapies

Combining state-of-the-art production, purification and analytics to optimize AAV manufacturing for clinical and commercial gene therapies

B Pence, R Snyder, K Torchilin
10 December 2019
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In-depth case study webinar: how MolMed achieved large-scale GMP production of LV and RV Vectors

In-depth case study webinar: how MolMed achieved large-scale GMP production of LV and RV Vectors

Giuliana Vallanti, Clive Glover
4 December 2019
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Key steps to industrialize your process and de-risk your pathway to commercialization in cell and gene therapy

Key steps to industrialize your process and de-risk your pathway to commercialization in cell and gene therapy

Behnam Baghbaderani
21 November 2019
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Meeting the scalability challenge of downstream viral vector purification

Meeting the scalability challenge of downstream viral vector purification

S Brittle, S Merino, X Fu et al.
12 November 2019
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Let’s talk integration

Let’s talk integration

N Bauer, M Dudley, J Ellis et al.
29 October 2019
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Rapid mycoplasma PCR QC testing for cell and gene therapies

Rapid mycoplasma PCR QC testing for cell and gene therapies

Renate Rosengarten, Angeliki Grammenos
24 October 2019
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Moving towards decentralized manufacturing of cell and gene therapy products through automation

Moving towards decentralized manufacturing of cell and gene therapy products through automation

I Johnston PhD, N Medcalf FREng FIChemE CChem CEng, Á Urbano-Ispizua PhD et al.
17 October 2019
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A bespoke solution to cell therapy manufacturing: the Cocoon platform

A bespoke solution to cell therapy manufacturing: the Cocoon platform

Matthew Hewitt
26 September 2019
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A lens on the final formulation and fill & finish process: considerations for process automation and device development

A lens on the final formulation and fill & finish process: considerations for process automation and device development

K Massey, M Covington, D Sethi
18 September 2019
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No room for error: preparing for inevitable variability in the cell and gene therapy supply chain

No room for error: preparing for inevitable variability in the cell and gene therapy supply chain

J Margolis, L Fox, R Hornung et al.
5 September 2019
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Accelerating advancement in gene therapy by improving downstream purification of viral vectors

Accelerating advancement in gene therapy by improving downstream purification of viral vectors

Orjana Terova, Hetal Brahmbhatt
27 August 2019
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Optimizing the workflow for therapeutic viral vectors – upstream and downstream

Optimizing the workflow for therapeutic viral vectors – upstream and downstream

S Hoover, L Chan, F Bellintani
18 July 2019
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Closing the production gap in gene therapy – A scalable helper virus-free AAV production platform

Closing the production gap in gene therapy – A scalable helper virus-free AAV production platform

N Faust, C Glover, A Topping et al.
11 July 2019
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NextGen now - Delivering tomorrow’s facilities today

NextGen now - Delivering tomorrow’s facilities today

Marc Pelletier, Ryan McDonough
25 June 2019
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Implementation of biopreservation best practices to address a critical component of cell and gene therapy manufacturing

Implementation of biopreservation best practices to address a critical component of cell and gene therapy manufacturing

Alireza Abazari MSc PhD
18 June 2019
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Enabling the next level of pluripotent stem-cell based therapies, from bench to commercialization

Enabling the next level of pluripotent stem-cell based therapies, from bench to commercialization

Puspa Pandey, Fan Yang
13 June 2019
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The power of ultra-high content and 3D imaging for the identification and characterisation of new CAR-T cell targets

The power of ultra-high content and 3D imaging for the identification and characterisation of new CAR-T cell targets

Olaf Hardt, Uwe Schröer
22 May 2019
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Gaining critical characterization insights for development of CAR-T therapies for solid tumors

Gaining critical characterization insights for development of CAR-T therapies for solid tumors

T Laskowski, J O’Rourke, J Krishnamurthy
16 May 2019
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Using patient outcomes data to inform and advance the development of emerging cell and gene therapies

Using patient outcomes data to inform and advance the development of emerging cell and gene therapies

D Henke, C Wilfong, M Pasquini
9 May 2019
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Optimizing process development to simplify manufacturing scale up of therapeutic viral vectors

Optimizing process development to simplify manufacturing scale up of therapeutic viral vectors

C Lorenz, V Kedinger, R Legmann et al.
17 April 2019
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Planning for success: emerging GMP-grade raw materials & technologies for cell therapy

Planning for success: emerging GMP-grade raw materials & technologies for cell therapy

S Kevlahan PhD, L Fox, Á Herrero Méndez PhD et al.
27 March 2019
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Critical components for developing and managing expansive, high-performing collection networks

Critical components for developing and managing expansive, high-performing collection networks

A Hines, R Smith, J Vitale et al.
14 March 2019
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Designing GMP-friendly cell and gene therapy manufacturing processes

Designing GMP-friendly cell and gene therapy manufacturing processes

M Papadimitrious, X Wang, B Murphy
6 March 2019
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Managing starting material stability to maximize manufacturing flexibility and downstream efficiency

Managing starting material stability to maximize manufacturing flexibility and downstream efficiency

Dominic Clarke, David Smith
21 February 2019
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Made-for-purpose manufacturing solutions - The key to commercialization

Made-for-purpose manufacturing solutions - The key to commercialization

N Bauer, B Dutra, S Leslie
31 January 2019
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Addressing the challenges of preserving cell and gene therapies

Addressing the challenges of preserving cell and gene therapies

Q Rafiq, A Schlinker, D Maier
18 January 2019
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Evaluation of Poros AAVX Pan-Affinity Resin for rAAV purification and cGMP Manufacturing

Evaluation of Poros AAVX Pan-Affinity Resin for rAAV purification and cGMP Manufacturing

Daniel Hurwit
18 December 2018
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Real-world insights into automated solutions for cell & gene therapy bioprocessing

Real-world insights into automated solutions for cell & gene therapy bioprocessing

B Levine, G Bauer, J Beltzer
12 November 2018
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Scalable, helper virus-free AAV production with stable CAP-GT producer cell lines

Scalable, helper virus-free AAV production with stable CAP-GT producer cell lines

Nicole Faust
8 November 2018
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Latest advances in automated platforms for autologous cell & gene therapy manufacturing

Latest advances in automated platforms for autologous cell & gene therapy manufacturing

E Abraham, D Kuijstermans, Y Shi
25 October 2018
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Strategies to relieve the burden on apheresis & collection centers

Strategies to relieve the burden on apheresis & collection centers

A Hines, G Whitehead, H Steinmetz
11 October 2018
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Making it happen: the road to commercial scale cell therapy manufacturing

Making it happen: the road to commercial scale cell therapy manufacturing

Y Levinson, T Richardson, I Friedrich Ben-Nun
27 September 2018
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Development of a purification step for several AAV serotypes using POROS™ CaptureSelect™ AAVX affinity chromatography

Development of a purification step for several AAV serotypes using POROS™ CaptureSelect™ AAVX affinity chromatography

Magali Toueille
19 July 2018
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Standardized techniques for navigating the cell and gene therapy supply chain

Standardized techniques for navigating the cell and gene therapy supply chain

Jamie Margolis, Mark Dudley
10 July 2018
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Advances in CAR-T manufacture – Bridging the commercialization gaps

Advances in CAR-T manufacture – Bridging the commercialization gaps

I Johnston, K Roy, G Russotti
28 June 2018
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Development & manufacture of next-generation viral vectors for gene therapy

Development & manufacture of next-generation viral vectors for gene therapy

Anandita Seth
20 June 2018
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Challenges of cell therapy manufacturing: automation and disposables – the hand and the glove

Challenges of cell therapy manufacturing: automation and disposables – the hand and the glove

Natasha Boghosian, Brian Hanrahan
10 May 2018
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Overcoming challenges with the supply of plasmid DNA & other raw materials for gene therapy manufacture

Overcoming challenges with the supply of plasmid DNA & other raw materials for gene therapy manufacture

J Brown PhD, M C McIntyre PhD, C Simpson et al.
17 April 2018
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Meeting scalability challenges for autologous cell-based manufacturing with automated closed-system solutions

Meeting scalability challenges for autologous cell-based manufacturing with automated closed-system solutions

Giulia Detela
8 March 2018
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GMP raw materials for cell therapy manufacture: what, when and how?

GMP raw materials for cell therapy manufacture: what, when and how?

J Stanton, J Paul Tomtishen III, D Wotta et al.
22 February 2018
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Commercial-scale viral vector manufacture: technical challenges & strategic implications

Commercial-scale viral vector manufacture: technical challenges & strategic implications

M Kelly, C Glover, R Snyder
14 February 2018
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Case studies in cell & gene therapy process optimization

Case studies in cell & gene therapy process optimization

David DiGiusto, Alaina Schlinker
18 January 2018
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Built to scale: strategic considerations to meet production demands in cell and gene therapy

Built to scale: strategic considerations to meet production demands in cell and gene therapy

S Ward, I Gaudet, H Embree
9 January 2018
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Cell & Gene Therapies for Rare Diseases: Navigating the Pathway to Market

Cell & Gene Therapies for Rare Diseases: Navigating the Pathway to Market

S Kili, G MacKay, S Washer
19 December 2017
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Automation of cell and gene therapy manufacturing: from vein to vein

Automation of cell and gene therapy manufacturing: from vein to vein

Q Rafiq, A Brown, A Chandra et al.
15 November 2017
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Cell & gene therapy manufacturing: key factors influencing manufacturing business models

Cell & gene therapy manufacturing: key factors influencing manufacturing business models

B Nelsen, K Warren, A Dulgar-Tulloch et al.
31 October 2017
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Optimizing supply chain design to ensure commercial success - The journey is as important as the destination

Optimizing supply chain design to ensure commercial success - The journey is as important as the destination

Simon Ellison, Kristen Franklin
12 September 2017
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Addressing the critical bottlenecks in the cell & gene therapy manufacturing pathway

Addressing the critical bottlenecks in the cell & gene therapy manufacturing pathway

P Zandstra, D Baksh, K Roy et al.
21 June 2017
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Advances in preserving, storing and managing the supply chain

Advances in preserving, storing and managing the supply chain

S Ellison, F Meacle, D Clarke
24 May 2017
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The latest developments in CAR-T cell manufacturing

The latest developments in CAR-T cell manufacturing

Isabelle Riviere
27 April 2017
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“One Word: Plastics” – The Role of Material Science in Cell Therapy Manufacturing

“One Word: Plastics” – The Role of Material Science in Cell Therapy Manufacturing

Natasha Boghosian, Katie Campbell
4 April 2017
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Advances in viral vector technology: Anc-AAV & evolutionary guided vector design

Advances in viral vector technology: Anc-AAV & evolutionary guided vector design

Luk H Vandenberghe, Dirk Grimm
28 February 2017
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Automation of cell & gene therapy manufacture: challenges, options & opportunities for innovation

Automation of cell & gene therapy manufacture: challenges, options & opportunities for innovation

Q Rafiq, B Hanrahan, B Mistry et al.
7 December 2016
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