Personalizing ctDNA monitoring: discovery to clinical implementation using dPCR

Wednesday 08:00 PDT / 11:00 EDT / 16:00 BST / 17:00 CEST

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Personalizing ctDNA monitoring: discovery to clinical implementation using dPCR

Live30 webinars pack the latest innovations and applications into a data-rich 30-minute session.

Enhance your cancer recurrence research capabilities with a proven workflow for longitudinal circulating tumor DNA (ctDNA) monitoring that delivers personalized molecular tracking for recurrence surveillance.

This webinar will demonstrate how you can achieve superior sensitivity compared to standard serum markers, enabling earlier detection of minimal residual disease immediately after surgery. As an attendee, you will gain practical expertise in dPCR-based liquid biopsy analysis that provides fast, cost-effective serial monitoring through rapid, absolute quantification of patient-specific ctDNA mutations.

The speaker will explore the assay design protocols step-by-step, including variant filtering thresholds, validation procedures, and optimal plasma volumes for reliable multi-target testing. They will also show you how to integrate broad genomic discoveries from whole exome sequencing with targeted dPCR validation to create efficient translational biomarker research pipelines.

Attend this webinar to:

Gain insights from real-world case studies demonstrating ctDNA dynamics that preceded conventional markers
Learn how dPCR enhances sensitivity and temporal resolution for ctDNA-based monitoring compared to conventional serum markers
Explore a ready-to-use workflow for designing, validating, and applying dPCR assays to longitudinal liquid biopsy study
Understand best practices in plasma handling, assay optimization, and sample planning to ensure robust, cost-effective monitoring

Adamo Pio D'Adamo

Associate Professor of Medical Genetics at University of Trieste

Adamo Pio d’Adamo is an Associate Professor of Medical Genetics at the University of Trieste, Italy, and coordinator of the PhD program in Personalized Medicine and Innovative Therapies at the same university. He also works in Medical Genetics Department at IRCCS Burlo Garofolo. He graduated in Biological Sciences and specialized in Applied Genetics at the University of Rome “La Sapienza.” His research focuses on the identification of genes responsible for Mendelian and complex diseases, with expertise in genomics, bioinformatics, and biostatistics. Over his career, he has authored more than 100 publications in international journals and collaborated with leading research institutes. He leads a research group dedicated to advancing genetic knowledge and translating discoveries into innovative healthcare solutions.

Nour Balasan

Postdoctoral Researcher at IRCCS Burlo Garofolo

Dr. Nour Balasan is a Postdoctoral Researcher in Medical Genetics at IRCCS Burlo Garofolo, Trieste. She holds a PhD in Personalized Medicine and Innovative Therapy from the University of Trieste. Her research focuses on applying advanced genomics and molecular technologies to cancer diagnostics, with a particular expertise in digital PCR for liquid biopsy. Dr. Balasan authored one of the first studies employing nanoplate digital PCR technology for the sensitive detection of circulating tumor DNA in gynecological cancers, highlighting its potential for early recurrence monitoring compared to conventional biomarkers. In addition, she has contributed to studies on extracellular vesicle proteomics and cancer metabolism. Her scientific interests bridge genomics, and innovative molecular diagnostics for precision oncology.

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