Exploring CAR-T manufacturing strategies - impact on quality, scale and cost

Thursday 08:00 PST / 11:00 EST / 16:00 GMT / 17:00 CET

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Exploring CAR-T manufacturing strategies - impact on quality, scale and cost

Live30 webinars pack the latest innovations and applications into a data-rich 30-minute session.

This webinar presents a head-to-head comparison of all-in-one and modular platforms for ex vivo CAR-T manufacturing across established 12-day and shortened 5-day workflows. Attendees will see comparative data on how each platform and process affects the critical quality attributes of the final product.

The session will also share proof-of-concept manufacturing cost estimates and experimental data from an automated, closed vial-filling system. Together, these provide a practical basis for fit-for-purpose platform and process selection.

Attend this webinar to:

Compare CQAs of CAR-T cells manufactured on all-in-one and modular platforms, including viability, yield, purity, transduction efficiency, memory phenotype, cytotoxicity, and cytokine release.
Weigh the strengths and limitations of each system in automation, closed processing, operational flexibility, and scale-up versus scale-out.
Review proof-of-concept direct manufacturing cost estimates for a range of all-in-one and modular workflows.
Evaluate data showing how automated, closed vial filling can increase fill accuracy while maintaining product quality.

Samuel Alsén, PhD

Lead Scientist at CCRM Nordic

Samuel is a Lead Scientist in CMC & Process Development at CCRM Nordic with a focus on immuno-oncology workflows. He holds a PhD in Immunology from the University of Gothenburg and has over 8 years of experience within the field of cell and gene therapy. Prior to joining CCRM Nordic, Samuel was working to establish tumor infiltrating lymphocyte (TIL) manufacturing at Sahlgrenska University Hospital with work spanning from process and analytic development, regulatory affairs and manufacturing operations. Building on his previous experiences, Samuel has specialized in automated and closed cell processing operations, supporting external and internal projects ranging from TIL and CAR-T development to 3D cultures of iPSCs.

In 43 Days

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