Platform-proof performance for AAV production in HEK293 cell lines

Tuesday 08:00 PST / 11:00 EST / 16:00 GMT / 17:00 CET

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Platform-proof performance for AAV production in HEK293 cell lines

AAV manufacturing is evolving fast, but process changes shouldn’t derail your performance. Too often, any change in the process triggers a new round of troubleshooting capsid quality (% full capsid) and genome titers.

In this webinar, a leading AAV manufacturing expert will explore the interaction of the critical components for production and reveal how the foundation of a flexible, high-performance media for growth and transfection creates a robust AAV platform, even as you swap plasmid designs and transfection chemistries. Discover practical strategies for optimizing parameters, maintaining HEK293 cell health, and achieving consistent results across multiple production setups.

Attend this webinar to:

Explore case studies demonstrating up to 7x higher AAV titers versus off-the-shelf production platforms
Learn how to evaluate and tune AAV process parameters using experimental design to improve yield and efficiency
Find out how to achieve viral titers >1e12 from crude lysate
Gain steps to maintain HEK293 cell health without complicated feed strategies

Sanjay Kumar, PhD

NA Head of Technical Excellence at Lonza Bioscience Media Solutions

Dr. Sanjay Kumar is the NA head of Technical Excellence at Lonza Bioscience Media Solutions. In this role, he serves as a customer-facing subject matter expert (SME), collaborating closely with customers and internal Lonza teams to ensure the customers receive the best possible experience with Lonza products. Sanjay brings over 25 years of combined experience, with more than half of it in industry, and a passion for discussing science and solving problems.

Prior to joining Lonza, he led the Custom Cell Engineering Services team at Thermo Fisher Scientific, partnering with customers to understand their needs and translate them into actionable strategies implemented by his scientific team. He brings a strong scientific foundation from his research on DNA replication and DNA damage responses in eukaryotes. His expertise spans cell culture development, genome editing, viral vector design, and advanced cell engineering.

In this webinar, Sanjay will discuss Lonza’s new TheraPEAK 293-GT® Media System for packaging AAVs. He will share key attributes and compelling data highlighting great AAV titers while offering the users freedom and flexibility in their workflows.

in 49

Days

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