Cell and Gene Therapy Insights Volume 12 Issue 4

CELL AND GENE THERAPY INSIGHTS

Volume 12 Issue 4

Cell and Gene Therapy Insights Volume 12 Issue 4

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Featuring

Issue Spotlight: Cell therapy manufacturing and supply chain
Other articles
Webinars

Cell therapy manufacturing and supply chain

Expert Insight

Towards intelligent supply networks: AI‑enabled simulation in the evolution of digital twins for autologous cell therapy manufacturing

Towards intelligent supply networks: AI‑enabled simulation in the evolution of digital twins for autologous cell therapy manufacturing

K Wang, Z Li, C White et al.

Commentary

Industrialization of cell therapy manufacturing: from artisanal process to scalable medicine

Industrialization of cell therapy manufacturing: from artisanal process to scalable medicine

Viewpoint

In vivo CAR-T: toward scalable and programmable immunotherapy

In vivo CAR-T: toward scalable and programmable immunotherapy

Kartika Venugopal

Interview

Building CAR‑T therapies with GMP‑first thinking

Building CAR‑T therapies with GMP‑first thinking

Stefanos Theoharis

Quality by design in CAR-T and TCR-T manufacturing: engineering around variability and QC constraints

Quality by design in CAR-T and TCR-T manufacturing: engineering around variability and QC constraints

articles

Innovator Insight

Bending the cost curve in AAV manufacturing via scalable platform innovation, productivity gains, and analytical insight

Bending the cost curve in AAV manufacturing via scalable platform innovation, productivity gains, and analytical insight

From bottleneck to breakthrough: how downstream process innovation, analytics, and AI are reshaping AAV‑based gene therapy

From bottleneck to breakthrough: how downstream process innovation, analytics, and AI are reshaping AAV‑based gene therapy

S Jeffers, S Mohanty, J Senaratne et al.

Viewpoint

Beyond the bespoke: could automation hold the key to the CAR‑T accessibility issue?

Beyond the bespoke: could automation hold the key to the CAR‑T accessibility issue?

Event Preview

Event Preview – Cell & Gene Therapy World Asia

Event Preview – Cell & Gene Therapy World Asia

Beyond CAR-T: Synthetic Immune Receptor T (SIR-T™) cells for solid tumors

Beyond CAR-T: Synthetic Immune Receptor T (SIR-T™) cells for solid tumors

Preet Chaudhary, MD, PhD

Strengthening ATMP process development through real-time metabolic monitoring and control

Strengthening ATMP process development through real-time metabolic monitoring and control

Arvind M. Padma, Nick Randall

Have we finally reached the end of in vitro testing? Positioning NGS in cell and gene therapy biosafety testing

Have we finally reached the end of in vitro testing? Positioning NGS in cell and gene therapy biosafety testing

Colette Côté, PhD

Improving manufacturing reliability in cell and gene therapy: practical operational strategies

Improving manufacturing reliability in cell and gene therapy: practical operational strategies

Francesca Vitelli

Novel resin design enables efficient enrichment of full AAV capsids by anion exchange chromatography

Novel resin design enables efficient enrichment of full AAV capsids by anion exchange chromatography

Martin Liao, PhD

Identifying and addressing key regulatory risks affecting cell therapy programs

Identifying and addressing key regulatory risks affecting cell therapy programs

C Chen, M Brewer, M Tejada et al.

New automated, closed system for cell therapy formulation and filling

New automated, closed system for cell therapy formulation and filling

New automated, closed system for cell therapy formulation and filling (APAC)

New automated, closed system for cell therapy formulation and filling (APAC)

The 24 months before CGT launch

The 24 months before CGT launch

Alexander Huber, PhD