CELL AND GENE THERAPY INSIGHTS

December 2024 Issue

Volume 10 Issue 11

Cell and Gene Therapy Insights Volume 10 Issue 11

Featuring

Issue Spotlight: Review of 2024 and previewing 2025
Vectors focus: Characterization and validation 2024
Other articles
Webinars

SPOTLIGHT

Review of 2024 and previewing 2025

Innovator Insight

Generation of novel AAV serotypes with enhanced infectivity, specificity, and lower toxicity via AAV capsid engineering platform

Generation of novel AAV serotypes with enhanced infectivity, specificity, and lower toxicity via AAV capsid engineering platform

Y Bu, Y Pan, Y Zhong et al.
3 December 2024
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Expert Roundtable

Preparing for success in gene therapy purification

Preparing for success in gene therapy purification

X Fu, A Sharma, A D Tustian et al.
5 December 2024
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Preparing for success in gene therapy analytical development

Preparing for success in gene therapy analytical development

Yan Zhi, Jing Li, Andres Castillo
2 December 2024
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Commentary

Personalization in advanced cellular ImmunoTherapeutics: activities in Ireland

Personalization in advanced cellular ImmunoTherapeutics: activities in Ireland

Athanasios Mantalaris, Nicki Panoskaltsis, Fiona Killard
13 January
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Viewpoint

Bio-printing in the context of end-to-end scalable tissue-engineered ATMP manufacturing

Bio-printing in the context of end-to-end scalable tissue-engineered ATMP manufacturing

Isaak Decoene, Ioannis Papantoniou
12 December 2024
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Industrializing cell therapy: how to bring curative therapies to all patients who need them?

Industrializing cell therapy: how to bring curative therapies to all patients who need them?

Jens Vogel
20 November 2024
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Overcoming the senescence barrier in stem cell expansion

Overcoming the senescence barrier in stem cell expansion

William Ying Khee Hwang
14 November 2024
Read

Vectors FOCUS

Characterization and validation 2024

Interview

Implementing platform-based technologies to scale viral vector manufacturing consistently and efficiently

Implementing platform-based technologies to scale viral vector manufacturing consistently and efficiently

Xueyuan Liu
19 December 2024
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Navigating the complexities of AAV and lentiviral vector characterization

Navigating the complexities of AAV and lentiviral vector characterization

Susumu Uchiyama
12 December 2024
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History and progress in viral vector particle size distribution analysis

History and progress in viral vector particle size distribution analysis

Steven Berkowitz
9 December 2024
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Journal articles

Expert Insight

‘Winning’ target product profiles for CAR-T cell therapies in oncology: critical success factors for commercially viable therapies

‘Winning’ target product profiles for CAR-T cell therapies in oncology: critical success factors for commercially viable therapies

Clare Hague, Louise Street-Docherty, Frances Pearson
19 December 2024
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Innovator Insight

Closed system solutions for cell and gene therapy manufacturing

Closed system solutions for cell and gene therapy manufacturing

Anette Funfak
5 December 2024
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From the lab to the bench: scaling up regulatory T cell therapy

From the lab to the bench: scaling up regulatory T cell therapy

Megan Levings, Hany Meås
26 November 2024
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Expert Roundtable

Early-stage analytical development strategies for cell therapy

Early-stage analytical development strategies for cell therapy

Ramon Mendoza, Kyle Carter, Seth Peterson
16 January
Read

FastFacts

Balancing precision and efficiency in cell therapy assays: low volume sampling for mycoplasma detection

Balancing precision and efficiency in cell therapy assays: low volume sampling for mycoplasma detection

Sharon Rouw
10 December 2024
Read

EBook

Highlights from the Cell and Gene Therapy Summits: what’s next for advanced therapies?

Highlights from the Cell and Gene Therapy Summits: what’s next for advanced therapies?

29 November 2024
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Webinar Digest

Demystifying AAV affinity capture: mapping AAV affinity ligand footprints with cryo-electron microscopy

Demystifying AAV affinity capture: mapping AAV affinity ligand footprints with cryo-electron microscopy

Nathaniel Clark
13 December 2024
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Corrigendum

Corrigendum to: Generation of novel AAV serotypes with enhanced infectivity, specificity, and lower toxicity via AAV capsid engineering platform

Corrigendum to: Generation of novel AAV serotypes with enhanced infectivity, specificity, and lower toxicity via AAV capsid engineering platform

Y Bu, Y Pan, Y Zhong et al.
19 December 2024
Read
Corrigendum to: Interpreting the new FDA draft potency guidance: an RNA cell therapy perspective

Corrigendum to: Interpreting the new FDA draft potency guidance: an RNA cell therapy perspective

Damian Marshall, Kayleigh Thirlwell
19 December 2024
Read

Webinars