Build protein and conjugate formulations that go the distance with Aunty

Wednesday 08:00 PDT / 11:00 EDT / 16:00 BST / 17:00 CEST

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Build protein and conjugate formulations that go the distance with Aunty

Live30 webinars pack the latest innovations and applications into a data-rich 30-minute session.

Protein formulation labs face challenges every day: more samples to test, increasingly complex candidates, and shorter timelines. Optimizing the safety, stability, and manufacturability of biologics, especially ones with developability issues, requires faster and smarter excipient screening across multiple biophysical parameters.

Aunty speeds up formulation studies using high-throughput, multi-attribute characterization of 8 µL samples in a 96-well SBS-format quartz plate. By combining full-spectrum DSF, SLS, and DLS in a single experiment, you can gather all the melting and aggregation data necessary to make faster, more informed decisions while improving efficiency.

Two case studies will illustrate Aunty’s flexibility for the thermal and colloidal stability characterization of proteins and conjugates. First, a DoE-based excipient screen of three antibodies and an enzyme identified major stability drivers. The second study tested ADCs with a common antibody backbone but different payloads and focused on how excipients tuned their stability.

Ross Walton

Sr. Marketing Applications Scientist at Unchained Labs

Ross Walton is a Sr. Marketing Applications Scientist for Biologics at Unchained Labs. He has published works on single-particle protein analysis by transmission electron microscopy and the interaction of the innate immune system and viruses in cancer. He did his undergraduate work at UC Berkeley and earned his PhD in Molecular Genetics and Microbiology from Duke University.

In 30 Days

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