Antibody Discovery & Engineering

Antibody Discovery & Engineering

  • The state of antibody engineering for conjugation 
    • How discovery is being rethought for the ADC era rather than borrowed from naked-mAb programs
  • How far can target diversification realistically go before validation and safety data become limiting?
  • The role of AI across the discovery workflow: hype versus demonstrated impact
  • Designing the antibody and the conjugate together
    • Breaking the silo between discovery and downstream development
  • What ‘developability’ means at the antibody stage, and how early choices cascade into CMC and clinic
  • Platform thinking: can one optimized scaffold serve multiple targets and payloads?
  • In-house discovery versus licensing engineered scaffolds, and what it means for differentiation