Preclinical & Clinical

Preclinical & Clinical

  • Identifying better correlates of protection
  • Harnessing advanced flow cytometry and sequencing tools
  • Validating and standardizing complex bioassays, e.g., T cell assays
  • Replacing animal models with robust in vitro models (e.g., organoids) for early phase development and potency determination
  • Improving prediction of reactogenicity before human trials e.g., cytokine release studies
  • Improving logistics and reducing costs to facilitate faster and more efficient clinical trials – including reliable point-of-care testing and decentralized testing solutions
  • Tailoring clinical research to specific populations e.g., maternal, older adults
  • Understanding the biological mechanisms of adverse events
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