Addressing sustainability and scalability bottlenecks in oligonucleotide

Nucleic Acid Insights 2026; 3(2), 132–136

10.18609/nuc.2026.015

Published: 30 March
Interview
Ewan Moody


“There is some really exciting work coming out in the enzymatic field, but for the time being, it still seems that chemistry has the upper hand.”

Jokūbas Leikauskas, Editor, Nucleic Acid Insights , speaks with Ewan Moody, Postdoctoral Research Associate, The University of Manchester, about the key sustainability and scalability bottlenecks in oligonucleotide manufacturing, focusing on solvent use, purification waste, and emerging chemical and enzymatic strategies for greener large-scale production.



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