mRNA

Streamlining quality assessment across IVT mRNA production

Nucleic Acid Insights 2026; 3(2)

10.18609/nuc.2026.016

Published: 31 March
Tech Showcase
Tingting Li


Integrated capillary electrophoresis workflows on the BioPhase 8800 platform enable streamlined, end-to-end quality assessment across IVT mRNA production, improving analytical consistency and early detection of critical quality issues.

In our interactive summary and video, Tingting Li (Cell and Gene Therapy Applications, Sciex) shows you how you can achieve:

✓
RSD <0.5% for supercoiled plasmid dimers
✓
0.1% RSD for linearized DNA purity measurements
✓
30 bp resolution for linearized DNA fragments
✓
~4 pg/µL sensitivity for DNA impurity detection
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Interactive summary preview


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