NUCLEIC ACID INSIGHTS

Meet the Nucleic Acid Insights Editorial Board

Meet the Nucleic Acid Insights Editorial Board

V Linko, Y Chen, J Counsell et al
30 April 2025
Infographic
What are your top predictions for the next five years in the nucleic acids field?

What are your top predictions for the next five years in the nucleic acids field?

J Yan, P Kowalski, J Weterings et al
30 April 2025
The Big Question
Meet the Nucleic Acids Insights Editorial Board: Jeske Smink

Meet the Nucleic Acids Insights Editorial Board: Jeske Smink

Jeske Smink
29 April 2025
Interview
Meet the Nucleic Acids Insights Editorial Board: Naim Nazef

Meet the Nucleic Acids Insights Editorial Board: Naim Nazef

Naim Nazef
29 April 2025
Interview
A scalable purification strategy for removal of dsRNA byproducts following IVT RNA production

A scalable purification strategy for removal of dsRNA byproducts following IVT RNA production

Nathaniel Clark
09 April 2025
Watch
Chemical modifications for therapeutic aptamers

Chemical modifications for therapeutic aptamers

H Rose, A Ansari, E A Hassan et al
07 April 2025
Review
For the many and the few: bringing ASO therapies to both mainstream and nano-rare indications

For the many and the few: bringing ASO therapies to both mainstream and nano-rare indications

Stanley Crooke
12 March 2025
Interview
Unveiling the potential of RNA-targeting therapies

Unveiling the potential of RNA-targeting therapies

Rabia Khan, Loïc Roux
05 December 2024
Review
Tackling the key challenges for therapeutic oligonucleotide manufacture: cost, scale, and sustainability

Tackling the key challenges for therapeutic oligonucleotide manufacture: cost, scale, and sustainability

Ben Andrews
26 November 2024
Interview
Bridging the translational gap: humanized liver models as predictive tools for RNA therapeutic success

Bridging the translational gap: humanized liver models as predictive tools for RNA therapeutic success

Matthew Baginski, Sara Donnelly
21 November 2024
Innovator Insight
mRNA characterization - from 5’ cap to poly (A): what IPRP-LC–MS can tell you

mRNA characterization - from 5’ cap to poly (A): what IPRP-LC–MS can tell you

Roxana Eggleston
06 November 2024
Watch
Advancing treatment of genetic diseases through engineered tRNA therapeutics

Advancing treatment of genetic diseases through engineered tRNA therapeutics

William Kiesman
24 September 2024
Interview
Delivering on the next generation of oligo therapies depends on overcoming, not ignoring, that sequence and chemistry are separable, but not independent

Delivering on the next generation of oligo therapies depends on overcoming, not ignoring, that sequence and chemistry are separable, but not independent

Chris Hart
08 August 2024
Viewpoint
Harnessing the potential of AI/ML to expand the horizons of the oligonucleotide therapeutics field

Harnessing the potential of AI/ML to expand the horizons of the oligonucleotide therapeutics field

Arijit Bhowmick
27 June 2024
Interview
Exploring issues and opportunities in the development of platform technologies for oligonucleotide manufacturing

Exploring issues and opportunities in the development of platform technologies for oligonucleotide manufacturing

Jeske Smink
03 June 2024
Interview
Insights into manufacturing lab-scale in vitro transcribed RNA modalities

Insights into manufacturing lab-scale in vitro transcribed RNA modalities

Andrew Varley
21 May 2024
Expert Insight
The chemistry and biology of oligonucleotide conjugation

The chemistry and biology of oligonucleotide conjugation

Sritama Bose, Peter L Oliver
28 March 2024
Commentary
Pushing the boundaries of siRNA targeting and delivery

Pushing the boundaries of siRNA targeting and delivery

Merle Fuchs
20 March 2024
Interview
Glimpsing the future of siRNA delivery strategies and the broader therapeutic application of oligonucleotides

Glimpsing the future of siRNA delivery strategies and the broader therapeutic application of oligonucleotides

Naim Nazef
12 March 2024
Viewpoint
Comparative analysis of nucleic acid delivery systems for gene therapy: assessing viral and non-viral approaches with emphasis on extracellular vesicles

Comparative analysis of nucleic acid delivery systems for gene therapy: assessing viral and non-viral approaches with emphasis on extracellular vesicles

Nizar Saad
28 February 2024
Commentary
Wall Street analyst’s perspective: taking the pulse of the nucleic acid-based prophylactic & therapeutic vaccine sectors

Wall Street analyst’s perspective: taking the pulse of the nucleic acid-based prophylactic & therapeutic vaccine sectors

Hartaj Singh
23 February 2024
Interview