Optimizing mRNA production: achieving 25 g/L mRNA yield with low dsRNA by integrating PAT

Rok Sekirnik

08 May 2025

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Meet the Nucleic Acid Insights Editorial Board

V Linko, Y Chen, J Counsell et al

30 April 2025

Infographic

What are your top predictions for the next five years in the nucleic acids field?

J Yan, P Kowalski, J Weterings et al

30 April 2025

The Big Question

Meet the Nucleic Acids Insights Editorial Board: Nizar Y Saad

Nizar Saad

29 April 2025

Interview

Exploring mRNA quality assessment using electrophoretic separation methods 

Chateen Krueger

23 April 2025

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The future is now: AI-enabled RNA–LNP discovery

Bowen Li

11 April 2025

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Novel srRNA vectors for customizable vaccine development

D S Spasova, S J Miyake-Stoner, G Picarda et al

10 April 2025

Short Communication

A scalable purification strategy for removal of dsRNA byproducts following IVT RNA production

Nathaniel Clark

09 April 2025

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Pandemic preparedness and the future of RNA therapeutics: RNA readiness and response

Duccio Medini

03 April 2025

Interview

Achieving high-quality, efficient mRNA synthesis for streamlined and cost-effective manufacturing

Helge Zieler, Khaled Yamout

27 March 2025

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Enhancing mRNA results through strategic RNA design and quality control

Ryan Lahr

27 March 2025

Podcast

Next-level LNP formulation with the Sunny Suite

Benjamin Knappett

26 March 2025

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Key considerations for successful clinical development of mRNA therapeutics

26 March 2025

Infographic

Predicting stability of conventional and mRNA-based vaccines

A Scaccia, C Saade, P Ballesta et al

20 March 2025

Research Article

Sharpen up your RNA and LNP quant with Stunner

Kevin Lance

19 March 2025

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Solving unique analytical challenges in mRNA-LNP bioprocessing with precise measurement methods

Nigel Herbert

11 March 2025

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Robotic gloveless isolator technology enhances regional production of advanced therapeutics

Zach Hartman, Peter Boman

27 February 2025

Innovator Insight

Addressing regulatory hurdles for individualized mRNA cancer immunotherapies: insights into the MHRA’s new guidance for developers

Francis Galaway

11 February 2025

Interview

Precision in production: optimizing monitoring and quality control for high-value plasmids

Oleksandr Karpenko

03 February 2025

Webinar Digest

Advancing mRNA-based cell therapies: the crucial role of mRNA optimization for therapeutic efficacy

Christian Bär, Ulrich Blache, Sandy Tretbar

23 January 2025

Viewpoint

Precise mRNA purity assessment for accelerated therapeutic development and release testing

Paul Mania, Joe Ferraiolo

13 January 2025

Innovator Insight