Monitoring of circulating CAR T cells

Annika is Miltenyi Biotec’s Product Manager responsible for the cell and gene therapy reagents portfolio, including CAR detection reagents and StainExpress™ dry antibody cocktails. During the past year, she has been working together with R&D to advance the development of tools that enable highly reliable and standardized cell and gene therapy analytics.

Sabine Hünecke received her Ph.D. in 2009 at the Goethe-Universität in Frankfurt, Germany, in the fields of stem cell transplantation and immunology. After her time as post-doc, in which she worked on optimizing cellular therapies their quality control and immune monitoring in patients, she became head of the laboratory for stem cell transplantation and immune therapies in 2012 at the University Hospital in Frankfurt. There, Sabine continues to work on the research of cellular immunotherapies, the immune monitoring of transplanted patients and the further development of cell purification methods and flow cytometric analysis for the characterization of stem cell transplants and cellular preparations.

Melanie Bremm performed her Ph.D. projects at the Goethe-Universität in Frankfurt, Germany, and then continued her Postdoc studies at the laboratories for stem cell transplantation and immunotherapies at the University Hospital in Frankfurt until 2012. Melanie took over the role as deputy head in the same laboratories in 2013 then and - as an example - since then is working on developing new cellular immunotherapies, assessing the cellular immune status in patients using flow cytometry and ensuring the production & quality control of stem cell preparations and immunotherapies under GMP.