Quantitative analysis of AAV capsid heterogeneity with mass photometry

Ensuring the efficacy and regulatory compliance of AAV-based gene therapies depends on critical quality attributes such as purity, potency, and safety. However, AAV preparations are often heterogeneous, containing capsid-related impurities that can reduce therapeutic effectiveness and increase production costs.  This 15-minute video presentation, accompanied by a poster summary, highlights how to achieve fast and accurate mass photometer analysis for characterizing AAV populations.

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