Scaling the supply chain 2024

Innovation in hematopoietic stem cell cryopreservation and cold chain management

Cell & Gene Therapy Insights 2024; 10(3), 345–362

DOI: 10.18609/cgti.2024.050

Published: 30 April
Expert Insight
Michele Prisciandaro, Michele Santodirocco, Giuseppe Fania, Michele Vacca

Over the last decade, hematopoietic cell transplantation (HCT) and the demand for cell therapies have expanded significantly due to their potential to treat various hematological and non-hematological malignancies [1][2][3][4]. The successful implementation and standardization of cryopreservation and cold chain management will be crucial in this context. What is the importance of cryopreservation in the era of new cellular therapies? What are the critical factors to manage?