Quantitative viral vector characterization: prioritizing genome vector integrity

Cell & Gene Therapy Insights 2024; 10(2), 83–89

DOI: 10.18609/cgti.2024.015

Published: 21 February
David Dobnik

Abi Pinchbeck, Commissioning Editor, Cell & Gene Therapy Insights, speaks to David Dobnik, Senior Research Associate at Biotechnological Hub of the National Institute of Biology, Slovenia. They discuss the viral vector characterization by different methods, the importance of measuring vector genome integrity in AAV analysis, and the advancement of methods in the quantification of residual host cell DNA.