Enabling instrument connectivity through digital automation
Cell & Gene Therapy Insights 2023; 9(6), 799–807
Automation of the manufacturing process for cell therapies could significantly increase manufacturing success rates while reducing manual touchpoints and labor. Innovative instrumentation to address the various unit operations across the manufacturing process have been developed at Thermo Fisher Scientific, which are specifically designed to facilitate digital integration and automation. Gibco™ CTS™ Cellmation™ Software for DeltaV™ System is an off-the-shelf, digital solution that allows users to connect cell therapy instruments within a common DeltaV network to control workflows across multiple instruments in a 21 CFR Part 11 compliant environment. This article will introduce a closed, modular end-to-end manufacturing process and demonstrate how instruments can be integrated, automated, and incorporated into existing workflows.