CELL AND GENE THERAPY INSIGHTS

March 2025 Issue

Volume 11 Issue 2

Cell and Gene Therapy Insights Volume 11 Issue 2
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Featuring

Issue Spotlight: Induced pluripotent stem cells (iPSCs)
Supply Chain focus: Raw/Starting Materials 2025
Other articles
Webinars

SPOTLIGHT

Induced pluripotent stem cells (iPSCs)
Sudhanshu Shekhar
Guest Editor:
Sudhanshu Shekhar, Principal Scientist at Cell Therapy Drug Product Process Development

Review

2D and 3D iPSC-CM models for studying cardiac toxicity and disease

2D and 3D iPSC-CM models for studying cardiac toxicity and disease

C W Heathershaw, K Shakeriastani, O L Latham et al.
8 April
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Commentary

Choosing the best path to patients: how to decide between in-house and outsourced iPSC therapy development and manufacturing

Choosing the best path to patients: how to decide between in-house and outsourced iPSC therapy development and manufacturing

Laura Koivusalo, Anni Mörö, Ross Macdonald
11 March
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Viewpoint

Investing in early-stage stem cell therapy developers

Investing in early-stage stem cell therapy developers

Stijn Heessen, Kristian Tryggvason
21 February
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Interview

Developing autologous iPSC-based therapies for Parkinson’s disease treatment

Developing autologous iPSC-based therapies for Parkinson’s disease treatment

Kim Raineri
28 February
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Supply Chain FOCUS

Raw/Starting Materials 2025

Review

Raw and starting materials for cellular and gene therapy products

Raw and starting materials for cellular and gene therapy products

Gary du Moulin
4 March
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Infographic

The reality of automation in CGT—Why closed systems matter: INFOGRAPHIC

The reality of automation in CGT—Why closed systems matter: INFOGRAPHIC

9 April
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Interview

Streamlining the supply chain: insights on raw material sourcing and quality by design

Streamlining the supply chain: insights on raw material sourcing and quality by design

Lara Silverman
19 March
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Journal articles

Innovator Insight

CAR-T manufacturing intensification: the next wave of CAR-T commercialization

CAR-T manufacturing intensification: the next wave of CAR-T commercialization

A Bersenev, E Kleiren, J Knighton et al.
3 April
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Robotic gloveless isolator technology enhances regional production of advanced therapeutics

Robotic gloveless isolator technology enhances regional production of advanced therapeutics

Zach Hartman, Peter Boman
27 February
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Achieving robust and scalable AAV empty/full capsid separation for gene therapy

Achieving robust and scalable AAV empty/full capsid separation for gene therapy

Julio Huato, Mark Schofield
26 February
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Expert Roundtable

Producing MSC-derived cell therapies: workflows, technologies, and case studies

Producing MSC-derived cell therapies: workflows, technologies, and case studies

I Malaspina, S Mei, T Ting et al.
28 March
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Interview

Navigating analytical and regulatory hurdles in early-phase clinical cell therapy development

Navigating analytical and regulatory hurdles in early-phase clinical cell therapy development

Vaibhav Patel
10 April
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Corrigendum

Corrigendum to: Efficient AAV purification with AAVX and AAV9 magnetic beads

Corrigendum to: Efficient AAV purification with AAVX and AAV9 magnetic beads

Shu Uin Gan
18 March
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Erratum

Erratum to: Therapeutic epigenome editing: safety and quality considerations of a new class of gene-targeted medicines

Erratum to: Therapeutic epigenome editing: safety and quality considerations of a new class of gene-targeted medicines

Houria Bachtarzi, Tim Farries
10 April
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Webinars