CELL AND GENE THERAPY INSIGHTS

November 2022 Issue

Volume 8 Issue 10

Cell and Gene Therapy Insights Volume 8 Issue 10

Featuring

Issue Spotlight: Cell therapy bioprocessing
Supply Chain focus: Raw & starting materials quality, sourcing and management 2022
Other articles
Webinars

SPOTLIGHT

Cell therapy bioprocessing
Alexey Bersenev
Guest Editor:
Alexey Bersenev, Assistant Professor of Clinical Laboratory Medicine at Yale University

Expert Roundtable

AAV process development & scale-up

AAV process development & scale-up

Catherine Cancian, Karen Doucette, Reinout Hesselink
7 March 2023
Read

Commentary

Cell therapy 101 (part 1)Challenges of early clinical development: a ‘thumbnail sketch’

Cell therapy 101 (part 1)Challenges of early clinical development: a ‘thumbnail sketch’

Michael D Leek
29 November 2022
Read

FastFacts

A flexible & fully automated process for CAR T cell manufacturing

A flexible & fully automated process for CAR T cell manufacturing

Sophia Lollies
11 November 2022
Read
Standardizing flow cytometric assays during cell manufacturing

Standardizing flow cytometric assays during cell manufacturing

Annika Graband
3 November 2022
Read

Viewpoint

Key considerations for early investment in the process development of cell-based therapeutics

Key considerations for early investment in the process development of cell-based therapeutics

Kelly Kemp, Sebastian Rieck
23 November 2022
Read
Producing cell-based therapeutic products with lot-to-lot consistency from highly variable starting cell products

Producing cell-based therapeutic products with lot-to-lot consistency from highly variable starting cell products

William E Janssen, Scott R Burger
2 November 2022
Read

Interview

Enabling GMP-ready cell sorting for cell and gene therapy manufacturing

Enabling GMP-ready cell sorting for cell and gene therapy manufacturing

Aditi Singh
8 February 2023
Read
Advancing cell therapy manufacturing towards industry 4.0

Advancing cell therapy manufacturing towards industry 4.0

Thomas Bollenbach
21 November 2022
Read
Enabling scalable manufacture of exosomes for future clinical & commercial requirements

Enabling scalable manufacture of exosomes for future clinical & commercial requirements

Peter Jones
22 October 2022
Read

Supply Chain FOCUS

Raw & starting materials quality, sourcing and management 2022

Innovator Insight

Cell & gene therapy orchestration: supply chain management in real-time

Cell & gene therapy orchestration: supply chain management in real-time

Andreas Göbel, Dr Camila Mendes
9 November 2022
Read

Viewpoint

Building resilience into post-pandemic cell & gene therapy supply chains

Building resilience into post-pandemic cell & gene therapy supply chains

Tiffany Clement, Cheryl Cox
18 November 2022
Read
The living cell supply chain: a product-specific, rational approach to management of cellular starting material donors & donations

The living cell supply chain: a product-specific, rational approach to management of cellular starting material donors & donations

William E Janssen, Scott R. Burger
18 November 2022
Read

Interview

Innovating in iPSC differentiation & engineering

Innovating in iPSC differentiation & engineering

Emily Titus
30 November 2022
Read
The drive for standardization in cellular starting material collection for cell therapy

The drive for standardization in cellular starting material collection for cell therapy

Anh Nguyen Jones
22 November 2022
Read

Journal articles

Expert Insight

Expanding the analytical toolbox to address complex cell-based therapies

Expanding the analytical toolbox to address complex cell-based therapies

Nathan C Manley, Samuel JI Blackford
18 November 2022
Read

Innovator Insight

Roadmap to success in AAV purification. In-process control, high throughput & novel column modalities as necessary means for control over scalable AAV process

Roadmap to success in AAV purification. In-process control, high throughput & novel column modalities as necessary means for control over scalable AAV process

R Žigon, M Tajnik Sbaizero, I Petrović Koshmak et al.
18 November 2022
Read
Process development excellence to de-risk & accelerate commercialization of cell & gene therapies

Process development excellence to de-risk & accelerate commercialization of cell & gene therapies

Behnam Ahmadian Baghbaderani
17 November 2022
Read
IsoTag™AAV: an innovative, scalable & non-chromatographic method for streamlined AAV manufacturing

IsoTag™AAV: an innovative, scalable & non-chromatographic method for streamlined AAV manufacturing

J Haley, J Jones, S Petraki et al.
3 November 2022
Read
Introducing Lonza’s AAV suspension transient transfection platform to de-risk your path to clinic

Introducing Lonza’s AAV suspension transient transfection platform to de-risk your path to clinic

Suparna Sanyal
21 October 2022
Read

Expert Roundtable

Diagnostic & therapeutic uses for extracellular vesicles: insights into a rapidly evolving field

Diagnostic & therapeutic uses for extracellular vesicles: insights into a rapidly evolving field

S Wild, J Correia, A de Fougerolles et al.
30 November 2022
Read

FastFacts

Driving the viral vector expressway: speeding through AAV manufacturing

Driving the viral vector expressway: speeding through AAV manufacturing

Andi Ushijima, Henry George
17 November 2022
Read

Poster

Feeder free expansion of a clinically relevant number of human NK cells

Feeder free expansion of a clinically relevant number of human NK cells

Erica Heipertz
10 November 2022
Read
Automated & scalable closed-system platform for cell isolation and activation

Automated & scalable closed-system platform for cell isolation and activation

Hany Meås
3 November 2022
Read

Podcast

Shear ignorance? Think again: breaking the perception of shear within viral vector manufacturing

Shear ignorance? Think again: breaking the perception of shear within viral vector manufacturing

Ratish Krishnan, Akshat Gupta
10 November 2022
Listen
CAR-T cells: from cancer to autoimmunity

CAR-T cells: from cancer to autoimmunity

Dimitrios Mougiakakos
11 October 2022
Listen

Webinars