Vol 8 Issue 01

CELL AND GENE THERAPY INSIGHTS

February 2022 Issue

Vol 8 Issue 01

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Featuring

Issue Spotlight: Preclinical and translational tools and strategies
Enhancing vector bioprocess scalability
Other articles

SPOTLIGHT

Preclinical and translational tools and strategies

Expert Insight

Considerations in establishing meaningful clinical endpoints in Duchenne muscular dystrophy & other neuromuscular disorders

Considerations in establishing meaningful clinical endpoints in Duchenne muscular dystrophy & other neuromuscular disorders

C Morris, R Dreghici, J Gonzalez
17 February 2022
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Interview

Keys to the successful preclinical-clinical translation of next-gen CAR-T cell therapy

Keys to the successful preclinical-clinical translation of next-gen CAR-T cell therapy

Devon J Shedlock
8 February 2022
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Advancing the application of organoids, tissue-on-a-chip, and other emerging <em> in vitro </em>models to support cell and gene therapy

Advancing the application of organoids, tissue-on-a-chip, and other emerging in vitro models to support cell and gene therapy

J Ekert, M Davies, P Candarlioglu
2 February 2022
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Vectors FOCUS

Enhancing vector bioprocess scalability

Innovator Insight

Platform optimization for efficient AAV purification: insights from a CDMO

Platform optimization for efficient AAV purification: insights from a CDMO

Vincent Ravault, Nicolas Laroudie
23 January 2022
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Expert Insight

Commercial-scale lentiviral vector manufacturing: is the myth busted?

Commercial-scale lentiviral vector manufacturing: is the myth busted?

Hanna Leinonen
31 January 2022
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Interview

Tackling scalability challenges in AAV manufacture

Tackling scalability challenges in AAV manufacture

Kyle Grant
31 January 2022
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FastFacts

Optimization of anion exchange purification for the large-scale production of plasmid DNA for gene therapy and DNA vaccine applications

Optimization of anion exchange purification for the large-scale production of plasmid DNA for gene therapy and DNA vaccine applications

Jenny England
15 February 2022
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Key considerations when adopting Droplet Digital PCR for viral vector manufacture

Key considerations when adopting Droplet Digital PCR for viral vector manufacture

Mark White
24 February 2022
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Podcast

Residual DNA testing in viral vector manufacture: exploring the challenges and solutions

Residual DNA testing in viral vector manufacture: exploring the challenges and solutions

Ilaria Scarfone, Mike Brewer
22 February 2022
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Journal articles

Innovator Insight

Magnetic selection for consistent cellular starting material in autologous cell therapy manufacture

Magnetic selection for consistent cellular starting material in autologous cell therapy manufacture

Rachel Perret, Kenneth Olsen
10 February 2022
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Developing stem cell therapies: expansion strategies and lessons learned

Developing stem cell therapies: expansion strategies and lessons learned

C Siler, S Mei, J Champagne
28 February 2022
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Commentary

Regenerative medicine: new paradigms

Regenerative medicine: new paradigms

Janet Lynch Lambert
1 February 2022
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Advancing patient access to cell & gene therapies: partnerships, pilots, & psyche

Advancing patient access to cell & gene therapies: partnerships, pilots, & psyche

Heather McDonald, PhD
1 February 2022
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Interview

Building from the ground up: business culture learnings for cell and gene therapy biotechs

Building from the ground up: business culture learnings for cell and gene therapy biotechs

James Noble
1 February 2022
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FastFacts

Characterization of a fit-for-purpose commercial rapid mycoplasma PCR test solution for routine quality control

Characterization of a fit-for-purpose commercial rapid mycoplasma PCR test solution for routine quality control

Jessica Hutcheson
3 February 2022
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Accelerating downstream analytical testing for gene therapy

Accelerating downstream analytical testing for gene therapy

Harald Ehlen
8 February 2022
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Poster

Advances in AAV process development

Advances in AAV process development

A Becerra, M Hebben, M Mercaldi
14 February 2022
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Optimizing downstream purification of high-quality plasmid DNA with POROS™ Chromatography Resins

Optimizing downstream purification of high-quality plasmid DNA with POROS™ Chromatography Resins

Alejandro Becerra, Johannes Buyel
14 February 2022
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Abeona Therapeutics evaluates a scalable suspension-based platform for production of viral vector for MPS-IIIA

Abeona Therapeutics evaluates a scalable suspension-based platform for production of viral vector for MPS-IIIA

Anne MacIntyre, Phil Maples
17 February 2022
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