Vol 6 Issue 3

CELL AND GENE THERAPY INSIGHTS

April 2020 Issue

Vol 6 Issue 3

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Featuring

Issue Spotlight: Viral vector bioprocessing & analytics: tools and innovations to meet future demand
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SPOTLIGHT

Viral vector bioprocessing & analytics: tools and innovations to meet future demand
Nolan Sutherland
Guest Editor:
Nolan Sutherland, Senior Scientist at Ring Therapeutics

Expert Insight

Lentiviral vector manufacturing process enhancement utilizing TFDF<sup>™</sup> technology

Lentiviral vector manufacturing process enhancement utilizing TFDF™ technology

T Williams, O Goodyear, L Davies et al.
5 May 2020
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Innovator Insight

Development and validation of quantitative real-time PCR for the detection of residual HEK-293 host cell DNA

Development and validation of quantitative real-time PCR for the detection of residual HEK-293 host cell DNA

Kara Norman
29 April 2020
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A reproducible, high-throughput platform to quantitatively study AAVs

A reproducible, high-throughput platform to quantitatively study AAVs

James White, Natalia Rodionova
28 April 2020
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Interview

Scaling AAV vector manufacture: overcoming roadblocks to the translation of gene therapies

Scaling AAV vector manufacture: overcoming roadblocks to the translation of gene therapies

Nicole Faust
15 May 2020
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Vector production in academia: obstacles and opportunities

Vector production in academia: obstacles and opportunities

Daniela Bischof, Emily Hopewell
5 May 2020
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Drawing parallels and cross-pollinating ideas between viral vector and vaccine fields

Drawing parallels and cross-pollinating ideas between viral vector and vaccine fields

Amine Kamen
5 May 2020
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What is ‘quality’ in viral vector manufacture? Strengths and limitations of current analytical tools

What is ‘quality’ in viral vector manufacture? Strengths and limitations of current analytical tools

Markus Hörer
5 May 2020
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How are fixed-bed bioreactors set to change viral vector processing?

How are fixed-bed bioreactors set to change viral vector processing?

Pim Velthof, Pranav Puri, Jolanda Van Vliet
28 April 2020
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Are suspension-based systems for cell and gene therapy key to commercial-scale manufacture?

Are suspension-based systems for cell and gene therapy key to commercial-scale manufacture?

Patrick Erbacher
27 April 2020
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Journal articles

Research Article

Cost analysis of vein-to-vein CAR T-cell therapy: automated manufacturing and supply chain

Cost analysis of vein-to-vein CAR T-cell therapy: automated manufacturing and supply chain

Adriana Lopes , Rob Noel, Andrew Sinclair
2 June 2020
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Innovator Insight

Key steps to industrialize your process and de-risk your pathway to commercialization

Key steps to industrialize your process and de-risk your pathway to commercialization

Behnam Baghbaderani
5 May 2020
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Addressing the current limitations of AAV gene therapies

Addressing the current limitations of AAV gene therapies

Dmitry A Kuzmin, Natalie R Johnston
1 May 2020
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Commentary

Trends in cell and gene therapy clinical development for rare and ultra-rare diseases

Trends in cell and gene therapy clinical development for rare and ultra-rare diseases

Sven Kili
29 April 2020
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Interview

Venture creation for cell and gene therapy and beyond

Venture creation for cell and gene therapy and beyond

Bruce Booth
4 April 2020
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Cell therapy’s role in defeating Covid-19

Cell therapy’s role in defeating Covid-19

Yaky Yanay
18 May 2020
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Commercial Insights

Cell & Gene Therapy Commercial Insight – February 2020

Cell & Gene Therapy Commercial Insight – February 2020

Mark Curtis, Richard Philipson
19 March 2020
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