NUCLEIC ACID INSIGHTS

Accelerate UF/DF of nucleic acids with real-time monitoring and automated process control 

Accelerate UF/DF of nucleic acids with real-time monitoring and automated process control 

Nigel Herbert
10 July 2025
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Optimizing plasmid DNA purification: strategies for reliable and expandable processes

Optimizing plasmid DNA purification: strategies for reliable and expandable processes

Christy Franco, Jasmina Puc
17 June 2025
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Assessing mRNA stability and integrity using mass photometry

Assessing mRNA stability and integrity using mass photometry

Maria Jacintha Victoria
04 June 2025
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Precise mRNA purity assessment for accelerated therapeutic development and release testing

Precise mRNA purity assessment for accelerated therapeutic development and release testing

Paul Mania, Joe Ferraiolo
04 June 2025
Webinar Digest
Incorporating digitalization in the conceptual design, research and development of plasmid biomanufacturing

Incorporating digitalization in the conceptual design, research and development of plasmid biomanufacturing

D Prazeres, A Azevedo, S Oliveira Duarte et al
29 May 2025
Commentary
AI-driven modular platform for peptide dendrimer lipid nanocarriers: streamlining and accelerating precision nucleic acid delivery

AI-driven modular platform for peptide dendrimer lipid nanocarriers: streamlining and accelerating precision nucleic acid delivery

Tristan Henser-Brownhill, Albert Kwok
22 May 2025
Viewpoint
Producing low-immunogenicity, high-stability mRNA with dsRNA reduction to <0.005% (LLOQ)

Producing low-immunogenicity, high-stability mRNA with dsRNA reduction to <0.005% (LLOQ)

Jen Dennin
21 May 2025
FastFacts
Optimizing mRNA production: achieving 25 g/L mRNA yield with low dsRNA by integrating PAT

Optimizing mRNA production: achieving 25 g/L mRNA yield with low dsRNA by integrating PAT

Rok Sekirnik
08 May 2025
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Solving unique analytical challenges in mRNA-LNP bioprocessing with precise measurement methods

Solving unique analytical challenges in mRNA-LNP bioprocessing with precise measurement methods

Nigel Herbert
01 May 2025
Innovator Insight
Meet the Nucleic Acid Insights Editorial Board

Meet the Nucleic Acid Insights Editorial Board

V Linko, Y Chen, J Counsell et al
30 April 2025
Infographic
What are your top predictions for the next five years in the nucleic acids field?

What are your top predictions for the next five years in the nucleic acids field?

J Yan, P Kowalski, J Weterings et al
30 April 2025
The Big Question
Meet the Nucleic Acids Insights Editorial Board: Nizar Y Saad

Meet the Nucleic Acids Insights Editorial Board: Nizar Y Saad

Nizar Saad
29 April 2025
Interview
Exploring mRNA quality assessment using electrophoretic separation methods  

Exploring mRNA quality assessment using electrophoretic separation methods 

Chateen Krueger
23 April 2025
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The future is now: AI-enabled RNA–LNP discovery

The future is now: AI-enabled RNA–LNP discovery

Bowen Li
11 April 2025
Interview
Novel srRNA vectors for customizable vaccine development

Novel srRNA vectors for customizable vaccine development

D S Spasova, S J Miyake-Stoner, G Picarda et al
10 April 2025
Short Communication
A scalable purification strategy for removal of dsRNA byproducts following IVT RNA production

A scalable purification strategy for removal of dsRNA byproducts following IVT RNA production

Nathaniel Clark
09 April 2025
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Pandemic preparedness and the future of RNA therapeutics: RNA readiness and response

Pandemic preparedness and the future of RNA therapeutics: RNA readiness and response

Duccio Medini
03 April 2025
Interview
Achieving high-quality, efficient mRNA synthesis for streamlined and cost-effective manufacturing

Achieving high-quality, efficient mRNA synthesis for streamlined and cost-effective manufacturing

Helge Zieler, Khaled Yamout
27 March 2025
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Enhancing mRNA results through strategic RNA design and quality control

Enhancing mRNA results through strategic RNA design and quality control

Ryan Lahr
27 March 2025
Podcast
Next-level LNP formulation with the Sunny Suite

Next-level LNP formulation with the Sunny Suite

Benjamin Knappett
26 March 2025
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Key considerations for successful clinical development of mRNA therapeutics

Key considerations for successful clinical development of mRNA therapeutics

26 March 2025
Infographic