CELL AND GENE THERAPY INSIGHTS

Technical and regulatory opportunities and challenges for cell and gene therapies in low earth orbit: a status report

Technical and regulatory opportunities and challenges for cell and gene therapies in low earth orbit: a status report

G du Moulin, I Sands, M Anne Snow et al
06 June 2025
Review
Overcoming translational challenges to advance cell therapy for neonatal brain injury

Overcoming translational challenges to advance cell therapy for neonatal brain injury

Mikey Creane
06 May 2025
Interview
Exploring translational challenges and strategies for advancing gene therapies in neurodegenerative diseases

Exploring translational challenges and strategies for advancing gene therapies in neurodegenerative diseases

Joseph Scarrott
17 April 2025
Interview
2D and 3D iPSC-CM models for studying cardiac toxicity and disease

2D and 3D iPSC-CM models for studying cardiac toxicity and disease

C W Heathershaw, K Shakeriastani, O L Latham et al
08 April 2025
Review
Looking to a future of multiplex cell engineering

Looking to a future of multiplex cell engineering

Marco Alessandrini
11 January 2024
Interview
Exploring the burgeoning role of non-viral approaches in the delivery of nucleic acids

Exploring the burgeoning role of non-viral approaches in the delivery of nucleic acids

Zhenghong Gao
05 January 2024
Interview
Biological & operational considerations for iPSC-derived cell production

Biological & operational considerations for iPSC-derived cell production

A Mogen, A Fernandez-Perez, J Wang et al
20 December 2023
Expert Roundtable
Building rings with spheres: a cell therapy approach to incontinence

Building rings with spheres: a cell therapy approach to incontinence

M Gilbert, S Čaputová, D Poli et al
07 December 2023
Commentary
Efficient reprogramming of fibroblasts into iPSCs using mRNA technology

Efficient reprogramming of fibroblasts into iPSCs using mRNA technology

Sebastian Diecke, Hannah Johannsen, Parivash Nouri
05 December 2023
Watch
An update on prime editing: recent advances and applications

An update on prime editing: recent advances and applications

Karl Petri, Julian Grünewald
23 November 2023
Commentary
Pioneering the development of point-of-care CAR T cell therapy manufacturing in Canada: experience from the CLIC-01 CD19 CAR T clinical trial

Pioneering the development of point-of-care CAR T cell therapy manufacturing in Canada: experience from the CLIC-01 CD19 CAR T clinical trial

Natasha Kekre
14 November 2023
Watch
HEK293 suspension culture in stirred 3D-systems for gene therapy development

HEK293 suspension culture in stirred 3D-systems for gene therapy development

Jorge Escobar
14 November 2023
FastFacts
Advancing multiplex base editing into the clinic

Advancing multiplex base editing into the clinic

Gopi Shanker
10 November 2023
Interview
Unravelling immunogenicity induced by Cas9 in gene therapy: a comprehensive commentary of current understanding and implications

Unravelling immunogenicity induced by Cas9 in gene therapy: a comprehensive commentary of current understanding and implications

Anna Lina Cavallo
08 November 2023
Commentary
Exploring the convergence of gene editing and RNAi in iPSC-derived allogeneic cell therapy

Exploring the convergence of gene editing and RNAi in iPSC-derived allogeneic cell therapy

Vlad Seitan
08 November 2023
Interview
Developing a multiplex gene editing approach targeting viral infection

Developing a multiplex gene editing approach targeting viral infection

TJ Cradick
08 November 2023
Interview
‘Soft’ genome editing using CRISPR nickases as a potential source of safer cell products

‘Soft’ genome editing using CRISPR nickases as a potential source of safer cell products

Zhen Li, Manuel Goncalves
20 October 2023
Expert Insight
Bringing the Sleeping Beauty transposon system to the clinic

Bringing the Sleeping Beauty transposon system to the clinic

Zoltán Ivics
18 October 2023
Interview
Cell sorting for enrichment of neuronal subpopulations – new perspectives for clinical research

Cell sorting for enrichment of neuronal subpopulations – new perspectives for clinical research

Thomas Andreska, Elisa Nent, Chengjun Jin
05 October 2023
Watch
How to expedite clinical development of oncology agents: overcoming complexities of early-phase oncology trials for ATMPs

How to expedite clinical development of oncology agents: overcoming complexities of early-phase oncology trials for ATMPs

Harriet Gray Stephens
29 September 2023
Viewpoint
Utilizing an automation-on-demand analytical tool for cancer immunotherapy

Utilizing an automation-on-demand analytical tool for cancer immunotherapy

Christoph Eberle
22 September 2023
Innovator Insight