CELL AND GENE THERAPY INSIGHTS

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Displacement chromatography for enrichment of rAAV genome-containing capsids using weak organic acid

Displacement chromatography for enrichment of rAAV genome-containing capsids using weak organic acid

T Zekovic, P Greback-Clarke, E Vorst et al
24 October 2024
Research Article
 Can novel bioreactors improve the cost of goods of viral vectors?

Can novel bioreactors improve the cost of goods of viral vectors?

Christos Stamatis, Alex Chatel, Suzanne Farid
20 June 2023
Research Article
 Validation of mRNA concentration determination by slope spectroscopy technology: a matrixed approach

Validation of mRNA concentration determination by slope spectroscopy technology: a matrixed approach

T Alvine, N Unsinn, J J Long et al
14 June 2023
Research Article
 Advanced therapies, hospital exemptions & marketing authorizations: the UK’s emerging regulatory framework for point-of-care manufacture

Advanced therapies, hospital exemptions & marketing authorizations: the UK’s emerging regulatory framework for point-of-care manufacture

Edison Bicudo, Irina Brass
23 February 2023
Research Article
 Consideration of quality by design principles in the use of sterilizing grade filters for clarification and final sterile filtration in adeno-associated virus applications

Consideration of quality by design principles in the use of sterilizing grade filters for clarification and final sterile filtration in adeno-associated virus applications

Morven McAlister, Alexander Lambropoulos
30 August 2022
Research Article
 Clarification of recombinant adeno-associated virus (rAAV) & lentivirus from adherent culture

Clarification of recombinant adeno-associated virus (rAAV) & lentivirus from adherent culture

Rajeshwar Chinnawar, Nicholas Marchand
01 May 2022
Research Article
 Characterization of a novel high-throughput, high-speed and high-precision plate-based image cytometric cell counting method

Characterization of a novel high-throughput, high-speed and high-precision plate-based image cytometric cell counting method

J Bell, Y Huang, H Qazi et al
14 May 2021
Research Article
 The necessity of automated manufacture for cell-based immunotherapies: a cost-based analysis

The necessity of automated manufacture for cell-based immunotherapies: a cost-based analysis

R McCoy, J Hasan, S Ward et al
10 June 2020
Research Article
 Cost analysis of vein-to-vein CAR T-cell therapy: automated manufacturing and supply chain

Cost analysis of vein-to-vein CAR T-cell therapy: automated manufacturing and supply chain

Adriana Lopes , Rob Noel, Andrew Sinclair
02 June 2020
Research Article
 A simple RP-HPLC method for the stability-indicating determination of N-acetyl-L-cysteine and N,N’-diacetyl-L-cystine in cell culture media

A simple RP-HPLC method for the stability-indicating determination of N-acetyl-L-cysteine and N,N’-diacetyl-L-cystine in cell culture media

AS Prakasha Gowda, Andrew Schaefer, Terry Schuck
08 April 2020
Research Article
 Regenerative medicine as a disruptive technology: implications for manufacturing & clinical adoption

Regenerative medicine as a disruptive technology: implications for manufacturing & clinical adoption

Geoffrey Banda, Joyce Tait, James Mittra
23 October 2019
Research Article
 Genomic-QC: large-scale genomic data mining to assess the quality of HiPSC lines

Genomic-QC: large-scale genomic data mining to assess the quality of HiPSC lines

Ravi Prabhkar More, Mahendra Rao, Odity Mukherjee
28 March 2019
Research Article
 Methylcellulose as a scaffold in the culture of liver-organoids for the potential of treating acute liver failure

Methylcellulose as a scaffold in the culture of liver-organoids for the potential of treating acute liver failure

A Chandrashekran, V Iansante, A Dhawan et al
18 December 2018
Research Article
 Scale-up of a perfusion-based dendritic cell generation process

Scale-up of a perfusion-based dendritic cell generation process

A Kozbial, H Weinstein, S K Murthy et al
18 December 2018
Research Article
 Establishment of a scalable manufacturing platform for in-silico-derived ancestral adeno-associated virus vectors

Establishment of a scalable manufacturing platform for in-silico-derived ancestral adeno-associated virus vectors

P Wang, V Bhat, W Dong et al
12 November 2018
Research Article
 A Novel Low Cost High Yield Clinical Scale Cell Separator

A Novel Low Cost High Yield Clinical Scale Cell Separator

PA Liberti, DW Ritter, TR Khristov
28 August 2018
Research Article
 Automated, spinning membrane filtration for preparation of mobilized leukapheresis products for CD34+ cell selection

Automated, spinning membrane filtration for preparation of mobilized leukapheresis products for CD34+ cell selection

Alaina Schlinker
30 October 2017
Research Article
 Daidzein analog 2l enhances osteogenic differentiation of BMSCs and ASCs seeded on PLGA scaffolds and heals critical size calvarial defects

Daidzein analog 2l enhances osteogenic differentiation of BMSCs and ASCs seeded on PLGA scaffolds and heals critical size calvarial defects

A Strong, M E Bateman, R B Jones et al
12 April 2017
Research Article
 Successful ex vivo expansion of pro-angiogenic cells from one single primitive HSC

Successful ex vivo expansion of pro-angiogenic cells from one single primitive HSC

A Oikawa, G Mangialardi, J Richards et al
06 July 2016
Research Article
 Characterization of Rhesus Macaque lung-resident multipotent stromal cells

Characterization of Rhesus Macaque lung-resident multipotent stromal cells

21 March 2016
Research Article