Redefining AAV manufacturing: achieve exceptional performance and quality with an innovative transient cell line

Live30 webinars are thirty-minute presentations designed to update you on the latest innovations, applications, and data in a fast yet interactive format.

Attend this webinar to learn about a novel HEK 293 suspension cell line designed for efficient and scalable rAAV production. Explore how it can seamlessly integrate into research workflows and large-scale GMP production, producing rAAVs across multiple serotypes, and how it can bring an innovative strategy to lower levels of encapsidated host cell DNA (hcDNA). 

As the AAV landscape evolves and stable producer cell lines emerge as future cell factories for prevalent diseases, R&D, preclinical studies, and diseases requiring small doses still demand flexible and rapid solutions. Therefore, transient cell lines, such as ELEVECTA™ transient cell line, are a necessary bridge to maintain productivity and quality. 

Learn how to resolve key challenges in AAV manufacturing, including:

• How cell line engineering can tackle encapsidated host cell DNA (hcDNA), an impurity that current downstream processing cannot remove
• The performance and quality advantages of ELEVECTA transient cell lines for rAAV production processes
• Insights into the integration of a transient cell line into existing workflows to streamline operations and improve efficiency 

Ines Goncalves

Head of Project Management at Cytiva

Ines Goncalves has held several scientific and management positions in the gene therapy and biotechnology sector. During her career, she has worked on advancing the development of stable cell lines for viral vector production and collaborated with global clients to pioneer innovative solutions for gene therapy manufacturing. Ines’s academic journey began with a Bachelor´s and Master´s degree in Molecular Biology and Genetics from the University of Lisbon, Portugal. She then pursued a PhD in Genetics at the University Hospital of Cologne, Germany, where her research focused on Neurobiology, specifically on spinal muscular atrophy. Recently, Ines completed an MBA degree from WHU – Otto Beisheim School of Management in Germany.

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Ines Goncalves

Head of Project Management at Cytiva

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