Cryo-processed leukapheresis using an automated closed system: a high-quality starting material for autologous and allogeneic CAR-T cell therapy manufacturing
Cell & Gene Therapy Insights 2025; 11(10), 1267
DOI: 10.18609/cgti.2025.147
Published: 26 November
FastFacts
![]() | CAR-T manufacturing relies on high-quality leukapheresis starting material, but manual cryopreservation introduces variability that can impact product consistency. This poster presents data evaluating the IntegriCell™ automated closed cryoprocess (ACP), designed to standardize leukapheresis cryopreservation while preserving cell viability and phenotype. The ACP workflow supports reproducible, cGMP-compliant processing for autologous and allogeneic CAR-T applications. This video presentation, accompanied by a poster summary, highlights how cryo-processed leukapheresis performed in an automated closed system can reliably generate high-quality starting material that supports robust, scalable manufacturing of CAR-T cell therapies.
|
