CELL AND GENE THERAPY INSIGHTS

May 2023 Issue

Volume 9 Issue 4

Cell and Gene Therapy Insights Volume 9 Issue 4

Featuring

Issue Spotlight: Gene delivery platform evolution part 1: viral
Supply Chain focus: Optimizing materials & consumables sourcing strategy through scale-up/-out 2023
Other articles
Webinars

SPOTLIGHT

Gene delivery platform evolution part 1: viral
Aravind Asokan
Guest Editor:
Aravind Asokan, Professor in Surgery, Director of Gene Therapy, Professor of Biomedical Engineering, Professor of Molecular Genetics and Microbiology, at Duke University School of Medicine

Foreword

Viral gene delivery platform evolution

Viral gene delivery platform evolution

Aravind Asokan
29 June 2023
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Expert Insight

Fine tuning AAV: machine learning the capsid

Fine tuning AAV: machine learning the capsid

Joseph Rabinowitz, Ravi Kalia
8 July 2023
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Commentary

Unraveling the origins of human adeno-associated virus 5

Unraveling the origins of human adeno-associated virus 5

Robert J Gifford, Robert M Kotin
14 June 2023
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Viewpoint

Harnessing the untapped potential of commensal viruses in genetic medicine

Harnessing the untapped potential of commensal viruses in genetic medicine

Joseph Cabral
4 May 2023
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Interview

At the cutting edge of AAV capsid engineering

At the cutting edge of AAV capsid engineering

Eric Kelsic, Adrian Veres
31 May 2023
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Utilizing AI to drive AAV-based gene delivery to the CNS

Utilizing AI to drive AAV-based gene delivery to the CNS

David Huss
31 May 2023
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Assessing recent milestones in AAV capsid discovery & development for CNS applications

Assessing recent milestones in AAV capsid discovery & development for CNS applications

Mathieu Nonnenmacher
9 May 2023
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Leveraging derisked AAV vector development & delivery approaches to enhance speed to market for rare disease gene therapies

Leveraging derisked AAV vector development & delivery approaches to enhance speed to market for rare disease gene therapies

Adrien Lemoine
28 April 2023
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Supply Chain FOCUS

Optimizing materials & consumables sourcing strategy through scale-up/-out 2023

Expert Roundtable

Cell culture in immune cell therapies: do more with less

Cell culture in immune cell therapies: do more with less

Anastasiya Smith, Josh Ludwig, David Hermanson
8 June 2023
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FastFacts

Navigating the gene & cell therapy regulatory landscape: when, why and how to deploy GMP gene editing materials

Navigating the gene & cell therapy regulatory landscape: when, why and how to deploy GMP gene editing materials

Michael Lau
13 June 2023
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Interview

Quantifying manufacturing uncertainty and developing digital tools for supply chain optimization

Quantifying manufacturing uncertainty and developing digital tools for supply chain optimization

Maria Papathanasiou
22 May 2023
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Journal articles

Innovator Insight

Advancing the purification of VSV-G pseudotyped lentiviral vectors by using affinity chromatography

Advancing the purification of VSV-G pseudotyped lentiviral vectors by using affinity chromatography

Pim Hermans, Frank Detmers
3 May 2023
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Expert Roundtable

Navigating evolving regulatory CMC guidance in the AAV gene therapy field

Navigating evolving regulatory CMC guidance in the AAV gene therapy field

M Brewer, A Cockroft, C Fuentes et al.
15 May 2023
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FastFacts

Designing viral clearance studies for CGT products according to ICH Q5A (R2): part 2

Designing viral clearance studies for CGT products according to ICH Q5A (R2): part 2

Tareq Jaber
19 May 2023
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Designing viral vector clearance studies for CGT products according to ICH Q5A (R2): part 1

Designing viral vector clearance studies for CGT products according to ICH Q5A (R2): part 1

Tareq Jaber
19 May 2023
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Simple analytical tools for detection of impurities in biologics produced using the Sf-baculovirus platform

Simple analytical tools for detection of impurities in biologics produced using the Sf-baculovirus platform

Maya Yovcheva
1 May 2023
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Webinars