One sample, whole picture: Analytical ultracentrifugation (AUC) has been foundational to protein characterization

Aggregation, self-association at formulation concentrations, and weak protein interactions all shape biotherapeutic safety and efficacy, yet column-based methods can dilute samples, dissociate weak complexes, and misreport aggregate content through matrix interaction.

This interactive poster shows how analytical ultracentrifugation (AUC) measures particles in native buffers — no matrix, no dilution, no standard curve — across mAb aggregates, concentrated formulations, protein–DNA stoichiometry, membrane proteins, and AAV capsid loading states.

Explore the interactive poster below

Please enter your email to access content Read now