Purification by design: an integrated view of bispecific antibody downstream processing

BioInsights 2026; 5–9

DOI: 10.18609/bio.2026.003

Published: 30 July
Interview
Wei Zhang

“…we are still somewhere between early industrialization and selective adoption.”

Ashling Cannon, Editor, BioInsights , speaks with Wei Zhang, Principal Scientist and Group Leader, Downstream Processing Group, A*STAR Bioprocessing Technology Institute (A*STAR BTI), about the downstream processing challenges unique to bispecific antibodies, including impurity separation, chromatography-induced aggregation, continuous bioprocessing, and the role of molecular design in enabling purification.