Developing mRNA vaccines for malaria elimination

Vaccine Insights 2023; 2(3), 97–100

DOI: 10.18609/vac.2023.018

Published: 11 April 2023
Nirbhay Kumar

“By targeting multiple stages of the parasite, both at the infection and transmission fronts, we hope to achieve a higher efficacy in reducing transmission at the population level, and ultimately local malaria elimination.”

The approval of the world’s first malaria vaccine in 2021 has been rightly celebrated as a breakthrough. However, while an approximately 30–40% reduction in hospital admissions is significant, the ultimate goal is to block transmission and eliminate the disease entirely – and the mRNA vaccine platform could be an important new weapon in our arsenal.