Exploring original antigenic sin as the basis for S. aureus vaccine failures

Vaccine Insights 2023; 2(1), 1–4

DOI: 10.18609/vac/2023.001

Published: 17 January
George Y Liu

The implication of the original antigenic sin concept for vaccine development is the need for a fundamental shift in working platform and a more complex way of rethinking how successful vaccines can be developed.