Innovations in process development and manufacturing for scaling ADCs

Bioconjugation Insights 2025; 1(5), 177–186

DOI: 10.18609/bci.2025.029

Published: 11 November
Innovator Insight
Juma Bridgewater, Sunny Zhang, Esohe Idusogie



“Future innovation in ADC manufacturing could significantly alter how we manage payloads and conjugation processes.”

Bioconjugation Insights hosted a panel of experienced biopharmaceutical leaders to discuss innovations and ongoing challenges in process development and manufacturing of ADCs. Juma Bridgewater, Sunny Zhang, and Esohe Idusogie explore the critical decision points in scaling ADC components, designing comparability studies, managing supply chain complexity, addressing capacity bottlenecks, and balancing speed, cost, and quality in an increasingly competitive field.